摘要
目的:系统评价代谢综合征(MetS)对泌尿系结石复发的影响。方法:计算机检索the Cochrane Library、PubMed、EMbase、Web of Science、万方数据库、中国知网、中国生物医学文献服务系统和维普数据库,搜集MetS与泌尿系结石复发影响的队列研究、病例对照研究,检索时限均为建库至2022年3月。由2名研究者独立筛选文献、提取资料和评价纳入研究的偏倚风险后,采用RevMan 5.3软件进行Meta分析。结果:共纳入7个研究,涉及384例MetS病人和664例非MetS病人。Meta分析结果显示:MetS能明显增加泌尿系结石复发的风险[RR=1.44,95%CI(1.25,1.67),P<0.00001]。亚组Meta分析结果显示:随访时间≤12个月泌尿系结石合并MetS的结石复发的风险增加[RR=1.66,95%CI(1.16,2.36),P=0.005];随访时间>12个月泌尿系结石合并MetS的结石复发的风险亦增加[RR=1.39,95%CI(1.19,1.63),P<0.0001]。结论:现有证据表明,泌尿系结石合并MetS能明显增加结石复发的风险并缩短复发周期。
Objective:To systematically evaluate the effect of metabolic syndrome(MetS)on urinary stone recurrence.Methods:The Cochrane Library,PubMed,EMbase,Web of Science,WanFang Database,CNKI,SinoMed and VIP were searched by computer to collect cohort studies and case-control studies on the effects of MetS and urinary stone recurrence.The retrieval time was from the inception to March 2022.After two researchers independently screened the literature,extracted the data and evaluated the bias risk of the included study,RevMan 5.3 software was used for Meta-analysis.Results:A total of 7 studies were included,including 384 MetS patients and 664 non-MetS patients.Meta-analysis results showed that MetS significantly increased the risk of urinary stone recurrence(RR=1.44,95%CI 1.25-1.67,P<0.00001).Subgroup Meta-analysis results showed that follow-up time≤12 months urinary stone combined MetS increased the risk of stone recurrence(RR=1.66,95%CI 1.16-2.36,P=0.005).Follow-up time>12 months,urinary stone combined with MetS increased the risk of recurrence(RR=1.39,95%CI 1.19-1.63,P<0.0001).Conclusion:Current evidence shows that urinary stone combined MetS can significantly increase the risk of stone recurrence and shorten the recurrence period.
作者
马玉婷
陈霞
MA Yuting;CHEN Xia(Health Tourism Institute,North Sichuan College of Preschool Teachers Education,Sichuan 628000 China)
出处
《循证护理》
2024年第7期1175-1180,共6页
Chinese Evidence-Based Nursing
关键词
代谢综合征
泌尿系结石
复发
队列研究
系统评价
Meta分析
循证护理
metabolic syndrome
urinary stone
recurrence
cohort study
systematic evaluation
Meta-analysis
evidence-based nursing
