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微创根管治疗中使用iRoot SP与AH PLUS材料对牙髓炎患者填充效果、炎症和疼痛的影响比较

Comparison of filling effect,inflammation,and pain in patients with pulpitis using iRoot SP and AH PLUS in minimally invasive root canal therapy
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摘要 目的:比较微创根管治疗中使用爱汝特SP生物陶瓷根管封闭糊剂(iRoot SP)与登士柏AH Plus根管充填材料(AH PLUS)对牙髓炎患者填充效果、炎症、疼痛的影响.方法:选择本院2023年1月至2023年6月收治的牙髓炎患者80例,随机分成对照组和观察组(n=40),微创根管治疗中对照组用AH PLUS,观察组用iRoot SP.治疗1 w后对比填充效果;治疗前、治疗1 w后采用酶联免疫吸附法测定龈沟液炎症因子肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)、C-反应蛋白(C-reactive protein,CRP)、细胞白介素-6(Interleukin-6,IL-6)水平;治疗前、治疗后12 h、24 h、72 h采用视觉模拟评分(Visual Analogu Scale,VAS)评估患者疼痛程度;治疗前、治疗1 w后采用牙周探针测定牙周袋深度(Periodontal pocket depth,PD)、牙龈指数(Gingival index,GI)、菌斑指数(Plaque index,PIL);观察记录治疗期间的不良反应.结果:观察组总适填率高于对照组(P<0.05);观察组治疗1 w后TNF-α、CRP、IL-6、治疗后12 h、24 h VAS评分以及治疗1 w后PD、GI、PIL均低于对照组(P<0.05);两组不良反应差异无统计学意义(P>0.05).结论:牙髓炎患者微创根管治疗中使用iRoot SP填充效果更好,改善炎症、疼痛、牙周指标更有效. Objective:To compare the effects of iRoot SP bioceramic root canal sealing paste(iRoot SP)and Denspar AH Plus root canal filling material(AH PLUS)on filling effect,inflammation,and pain in patients with pulpitis in minimally invasive root canal treatment.Methods:Eighty patients with pulpitis admitted to our hospital from January 2023 to June 2023 were randomly divided into a control group and an observation group(n=40).In minimally invasive root canal therapy,AH PLUS was used in the control group and iRoot SP in the observation group.The filling effect was compared after 1 week of treatment.Tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),and Interleukin-6(IL-6)levels were detected by enzyme-linked immunosorbent assay before and after 1 week of treatment.Visual Analog Scale(VAS)was used to evaluate the pain degree of patients before treatment,12 h,24 h,and 72 h after treatment.Periodontal pocket depth(PD),gingival index(GI),and plaque index(PIL)were measured by periodontal probe before and after 1 week of treatment.The adverse reactions were observed and recorded during treatment.Results:The total fit rate of the observation group was higher than that of the control group(P<0.05).After 1 week of treatment,TNF-α,CRP,IL-6,12 h,24 h VAS scores,and PD,GI,and PIL were lower after 1 week of treatment in the observation group than in the control group(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion:The filling effect of iRoot SP in minimally invasive root canal treatment of pulpitis patients is better,and it is more effective in improving inflammation,pain,and periodontal indexes.
作者 袁宝乘 Yuan Bao-cheng(Department of Stomatology,Yongfeng People's Hospital,Ji'an 331500,Jiangxi,China)
出处 《四川生理科学杂志》 2024年第3期592-594,603,共4页 Sichuan Journal of Physiological Sciences
关键词 微创根管治疗 牙髓炎患者 根管充填材料 填充效果 Minimally invasive root canal therapy Patients with pulpitis Root canal filling material Filling effect

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