摘要
目的系统评价老年胃肠道肿瘤患者术前衰弱对功能状态和生活质量的影响。方法计算机检索中文数据库中国知网(CNKI)、万方(WanfangData)、维普(VIP)、中国生物医学文献数据库(CBM)和英文数据库Pubmed、Embase、Web of Science、Cochrane Library、CINAHL中老年胃肠道肿瘤患者衰弱与功能状态和生活质量关系的研究,检索时间为建库至2023年2月21日。由两名研究者独立进行文献筛选、资料提取以及质量评价,随后对纳入文献进行描述性分析。结果共纳入8篇前瞻性队列研究,其中1篇为中等质量,另7篇为高等质量。各研究对患者功能状态和生活质量选用的评估工具有差异,功能状态的评估主要使用的是ADL量表、IADL量表以及Barthel指数,生活质量的评估工具包含SF-12量表、EORTC QLQ-C30、EQ-5D量表等。描述性分析结果显示,老年胃肠道肿瘤患者术前衰弱会导致出院后低生活质量,但对该人群出院后的功能状态无明显影响。结论未来需要选择适宜的评估工具对老年胃肠道肿瘤患者的功能状态和生活质量进行评估,要开展更多的前瞻性队列研究进一步验证该人群的术前衰弱状态与其出院后功能状态和生活质量的关系。
Objective To systematically evaluate the effects of preoperative frailty status on functional status and quality of life in elderly patients with gastrointestinal tumors.Methods Sys-tematic review of literature was conducted using nine electronic databases:CNKI,Wanfang Da-ta,VIP,CBM,Pubmed,Embase,Web of Science,Cochrane Library,CINAHL,and the stud-ies about the relationship between functional status and quality of life in elderly patients with gas-trointestinal tumors.The search was conducted from the date of database creation to 21 February 2023.Literature screening,data extraction and quality evaluation were carried out independently by two researchers,and then descriptive analysis of included studies.Results A total of eight prospective cohort studies were included,of which one was of moderate quality and the other sev-en were of high quality.The assessment tools of functional status and quality of life of patients in different studies are different.The ADL scale,IADL scale and Barthel index were mainly used for the assessment of functional status,and the tools for the assessment of quality of life contain-ing SF-12 scale,EORTC QLQ-C30,and EQ-5D scale.The results of descriptive analysis showed that preoperative frailty in elderly patients with gastrointestinal tumors led to low quality of life af-ter discharge,but had no significant effect on functional status after discharge.Conclusion In the future,there is a need to select appropriate assessment tools to evaluate the functional status and quality of life in elderly patients with gastrointestinal tumors,and because of the small num-ber of included studies,more high-quality prospective cohort studies should be conducted in the future to further validate the relationship between preoperative frailty and post-discharge function-al status and quality of life in this population.
作者
姚家菲
郭淑丽
王玉钰
许诺
郭爱敏
YAO Jiafei;GUO Shuli;WANG Yuyu;WU Nuo;GUO Aimin(School of Nursing,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing,100144;Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730)
出处
《中西医结合护理》
2024年第3期124-131,共8页
Chinese Journal of Integrative Nursing
关键词
术前衰弱
胃肠道肿瘤
功能状态
生活质量
preoperative frailty
gastrointestinal tumors
functional status
quality of life
