摘要
结直肠腺瘤作为结直肠癌的重要癌前病变,内镜下切除虽作为首要治疗手段,但腺瘤复发率较高,如何预防腺瘤的发生,阻断腺瘤癌序列的进展是我们的研究方向。中医理论中“痰浊内阻”是结肠腺瘤发生与复发的主要原因,并且“痰浊”与“脂代谢”二者联系密切,因此本文将就“痰浊内阻”与“脂代谢紊乱”在结肠腺瘤中的联系进行讨论,探讨结肠腺瘤“痰浊内阻”的现代生物学内涵。通过探讨二者之间的联系可为临床治疗结肠腺瘤提供思路,同时还可将其运用到其他有关痰浊内阻、脂代谢紊乱的疾病中,以扩展临床诊治思维。
Colorectal adenoma is an important precancerous lesion of colorectal cancer.Although endoscopic resection of colorectal adenomas is the primary treatment method,the recurrence rate is relatively high.How to prevent the occurrence of adenomas and block the progression of the adenoma-cancer sequence is our research direction.In traditional Chinese medicine theory,“internal obstruction of phlegm turbidity”is the main reason for the occurrence and recurrence of colorectal adenoma,and“phlegm turbidity”is closely related to“lipid metabolism”.Therefore,in order to provide ideas for the clinical treatment of colon adenomas,this article discusses the association between“phlegm turbidity”and“lipid metabolism disorder”in colonic adenomas,and explore the modern biological connotation of“phlegm turbidity”.At the same time,this idea can also be applied to other diseases related to internal obstruction of phlegm turbidity and lipid metabolism disorders,in order to expand clinical diagnosis and treatment thinking.
作者
王洁
唐莉
缪伟峰
杨勤
WANG Jie;TANG Li;MIAO Weifeng;YANG Qin(Department of Spleen and Stomach Diseases,Nanjing Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing 210022,China;Zhenjiang Clinical Medical Research Center of Spleen and Stomach diseases,Zhenjiang Hospital of Traditional Chinese Medicine of Nanjing University of Chinese Medicine Zhenjiang 212008,China)
出处
《中医药学报》
CAS
2024年第4期12-17,共6页
Acta Chinese Medicine and Pharmacology
基金
江苏省中医药科技发展计划面上项目(MS2023055)
南京市卫生科技发展专项资金项目(ZKX21058)
南京市卫生科技发展专项资金项目(YKK20163)
镇江市中医院中医脾胃病临床医学研究中心开放研究课题(SSPW2022-KF05)
镇江市中医院中医脾胃病临床医学研究中心课题(SSPW2022-KF01)。
关键词
结肠腺瘤
痰浊内阻
脂代谢
复发与恶变
Colonic adenoma
Internal obstruction of phlegm and turbidity
Lipid metabolism
Recurrence and malignancy
