摘要
目的:分析环磷腺苷葡胺联合硝酸异山梨酯治疗慢性肺源性心脏病(简称慢性肺心病)合并心力衰竭的效果。方法:选取2016年1月—2021年12月黔南州人民医院收治的慢性肺心病合并心力衰竭患者72例作为研究对象,依据随机数字表法分为两组,各36例。对照组给予常规综合治疗,治疗组在对照组基础上应用环磷腺苷葡胺、硝酸异山梨酯治疗。比较两组治疗效果。结果:治疗组治疗总有效率高于对照组,差异有统计学意义(P=0.032)。治疗组心电图改善总有效率高于对照组,差异有统计学意义(P=0.003)。两组不良反应总发生率比较,差异无统计学意义(P=0.380)。结论:环磷腺苷葡胺联合硝酸异山梨酯治疗慢性肺心病合并心力衰竭的效果较好,可有效改善患者心肺功能,且治疗安全性较高。
Objective:To analyze the effect of meglumine adenosine cyclophosphate combined with isosorbide dinitrate in the treatment of chronic pulmonary heart disease with heart failure.Methods:A total of 72 patients with chronic pulmonary heart disease and heart failure admitted to Qiannan People's Hospital from January 2016 to December 2021 were selected as the study subjects.They were divided into two groups according to random number table method,with 36 cases in each group.The control group received conventional comprehensive treatment,and the treatment group received meglumine adenosine cyclophosphate and isosorbide dinitrate treatment on the basis of the control group.The treatment effects were compared between the two groups.Results:The total effective rate of treatment in the treatment group was higher than that in the control group,and the difference was statistically significant(P=0.032).The total effective rate of electrocardiogram improvement in the treatment group was higher than that in the control group,and the difference was statistically significant(P=0.003).There was no significant difference in the total incidence of adverse reactions between the two groups(P=0.380).Conclusion:The combination of meglumine adenosine cyclophosphate with isosorbide dinitrate has good effects in the treatment of chronic pulmonary heart disease with heart failure,and can effectively improve the cardiopulmonary function of patients,with a high treatment safety.
作者
杨正金
方银
罗普荣
吴熙
Yang Zhengjin;Fang Yin;Luo Purong;Wu Xi(Department of Respiratory and Critical Care Medicine,Qiannan People's Hospital,Duyun 558000,Guizhou Province,China)
出处
《中国社区医师》
2024年第6期11-13,共3页
Chinese Community Doctors
关键词
环磷腺苷葡胺
硝酸异山梨酯
慢性肺源性心脏病
心力衰竭
Meglumine adenosine cyclophosphate
Isosorbide dinitrate
Chronic pulmonary heart disease
Heart failure
