摘要
目的探究多囊卵巢综合征(PCOS)患者甲状腺素水平及其临床意义。方法选取40例PCOS患者作为观察组,依据血清促甲状腺激素(TSH)水平将患者分为低水平组(16例,TSH为<2.5mIU/L)、中水平组(14例,TSH为2.5~4mIU/L)、高水平组(10例,TSH为>4mIU/L)。另选取本院同期健康体检者40例作为对照组。比较甲状腺素、糖脂代谢水平。结果观察组三碘甲状腺原氨酸(T_(3))、甲状腺素(T_(4))、游离三碘原氨酸(FT_(3))水平较对照组低,TSH、空腹胰岛素(FINS)水平较对照组高(P<0.05)。三组促黄体生成素(LH)、卵泡刺激素(FSH)、FINS水平两两比较差异均有统计学意义(P<0.05)。结论PCOS患者甲状腺素水平会发生明显改变,且TSH水平越高,患者性激素分泌、糖脂代谢异常程度越高,临床需予以重视,尽早监测。
Objective To explore the thyroid level and its clinical significance in patients with polycystic ovary syndrome(PCOS).Methods 4o PCOS patients were selected as the observation group,and according to the serum TSH level,the patients were divided into a low level group(16 cases,TSH<2.5 mIU/L),a medium level group(14 cases,TSH<2.5~4 mIU/L),and a high level group(10 cases,TSH>4 mIU/L).Another 40 healthy subjects were selected as control group.The levels of thyroxine,glucose and lipid metabolism were compared.Results The levels of triodothyronine(T_(3)),thyroxine(T_(4))and free triodothyronine(FT_(3))in observation group were lower than those in control group,and the levels of TSH and fasting insulin(FINS)in observation group were higher than those in control group(P<0.05).There were significant differences in luteinizing hormone(LH),follicle stimulating hormone(FSH)and FINS levels among the three groups(P<0.05).Conclusion The level of thyroxine in PCOS patients will change significantly,and the higher the level of TSH,the higher the abnormal level of sex hormone secretion and glucose and lipid metabolism of patients,which should be paid attention to and monitored as soon as possible.
作者
魏晓丽
Wei Xiaoli(Department of Obstetrics and Gynecology,Bejing Huairou Hospital,Beijing 101400,China)
出处
《实用妇科内分泌电子杂志》
2024年第1期29-31,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
多囊卵巢综合征
甲状腺素
性激素
糖脂代谢
Polycystic ovary syndrome
Thyroid hormone
Sexual hormones
Glycolipid metabolism
