摘要
目的评估无创呼吸机应用在急性心力衰竭(AHF)合并呼吸衰竭(RF)患者治疗中的效果及对心肺功能、肌酸激酶同工酶(CK-MB)的影响。方法研究时间段2021年1月至2022年8月,研究对象80例AHF合并RF患者,分组方法:随机数字表法[对照组(40例,行常规药物治疗)、观察组(40例,加用无创呼吸机治疗)],评价组间治疗有效性、血气结果、心肺功能、血清学指标。结果(1)较之对照组(75.00%),观察组治疗有效率(95.00%)更高,P<0.05;(2)治疗前,组间血气结果[酸碱度(pH)、动脉血氧饱和度(SaO_(2))、动脉血氧分压(PaO_(2))]、心肺功能[心率(HR)、心脏指数(CI)、左室射血分数(LVEF)、用力肺活量(FVC)、最大呼气容量(PEF)、1(LVEF)、用力肺活量(FVC)]、血清学指标[CK-MB、氨基末端B型钠尿肽原(NT-pro BNP)、心肌肌钙蛋白I(cTnI)]无差异,P>0.05;治疗后,观察组血气结果(pH、SaO_(2)、PaO_(2))、心肺功能(HR、CI、LVEF、FVC、PEF、FEV1)、血清学指标(CK-MB、NT-pro BNP、cTnI)更佳,P<0.05。结论对AHF合并RF患者行无创呼吸机治疗,能够改善心肺功能、血气分析结果,降低CK-MB、NT-pro BNP、cTnI水平,提高治疗有效性,值得推广。
Objective To evaluate the effectiveness of non-invasive ventilation in the treatment of patients with acute heart failure(AHF)and respiratory failure(RF),as well as its impact on cardiopulmonary function and creatine kinase isoenzyme(CK-MB).Method A total of 80 patients with AHF complicated with RF from January 2021 to August 2022 were included.They were randomly divided into a control group(40 cases included,treated with conventional medication)and an observation group(40 cases included,treated with non-invasive ventilation)using a random number table method.The treatment effectiveness,blood gas results,cardiopulmonary function,and serological indicators between the groups were evaluated.Result(1)Compared with the control group(75.00%),the observation group had a higher treatment effective rate(95.00%),with P<0.05;(2)Before treatment,there was no difference in inter group blood gas results[pH,arterial oxygen saturation(SaO_(2)),arterial partial pressure of oxygen(PaO_(2))],cardiopulmonary function[heart rate(HR),cardiac index(CI),left ventricular ejection fraction(LVEF),forced vital capacity(FVC),maximum expiratory volume(PEF),forced expiratory volume at 1 second(FEV1)],serum indicators[CK-MB,N-terminal B-type natriuretic peptide(NT pro BNP),and cardiac troponin I(cTnI)],with P>0.05;After treatment,the observation group showed better blood gas results(pH,SaO_(2),PaO_(2)),cardiopulmonary function(HR,CI,LVEF,FVC,PEF,FEV1),and serum indicators(CK-MB,NT pro BNP,cTnI),with P<0.05.Conclusion Non invasive ventilation therapy for patients with AHF combined with RF can improve cardiopulmonary function,blood gas analysis results,reduce CK-MB,NT pro BNP,cTnI levels,and enhance treatment effectiveness,which is worth promoting.
作者
向常娥
XIANG Chang-e(Zhongnan Hospital Xingshan Hospital of Wuhan University,Xingshan 443700,Hubei Province,China)
出处
《罕少疾病杂志》
2024年第4期39-41,共3页
Journal of Rare and Uncommon Diseases
关键词
无创呼吸机
急性心力衰竭
呼吸衰竭
心肺功能
肌酸激酶同工酶
Non-invasive Ventilator
Acute Heart Failure
Respiratory Failure
Cardiopulmonary Function
Creatine Kinase Isoenzyme
