摘要
目的疑诊多囊卵巢综合征(PCOS)的病人,探讨联合检测血清抗苗勒激素(AMH)及性激素在诊断中的价值。方法选取我院首次就诊并确诊为多囊卵巢综合征的50例患者,作为观察组;并从我院健康管理中心同期体检的患者中抽取58例体检者作为对照组。两组患者血清中的AMH、卵泡刺激素(FSH)、促黄体生成素(LH)、雌激素(E2)、睾酮(T)的水平均采用电化学发光免疫分析技术进行测定后,再进行相关统计学分析。结果观察组的AMH、LH、T的平均水平高于对照组,而FSH的平均水平低于对照组,组间差异具有统计学意义(P<0.05),E2水平虽低于对照组,但组间差异不具有统计学意义(P>0.05)。与其他性激素相比较,AMH对PCOS诊断的灵敏度(86.00%)较高,且与性激素联合检测后,联合诊断的价值高于单项检测。结论血清AMH对多囊卵巢综合征的诊断有意义,并且联合性激素检测后诊断价值更高。
Objective To investigate the value of serum AMH combined with sex hormone in the diagnosis of polycystic ovary syndrome(PCOS).Methods 50 patients with polycystic ovary syndrome first diagnosed in our hospital were selected as the observation group.In addition,58 healthy subjects in the health management center of our hospital during the same period were selected as the control group.The serum levels of AMH,follicle stimulating hormone(FSH),luteinizing hormone(LH),estrogen(E2)and testosterone(T)in the two groups were detected by electrochemiluminescence immunoassay,and then statistically analyzed.Results The average level of AMH,LH and T in the observation group was higher than that in control group,while the average level of FSH was lower than that in control group,the difference was statistically significant(P<0.05).The level of E2 was lower than that in control group,but the difference was not statistically significant(P>0.05).Compared with other sex hormones,the sensitivity of AMH in the diagnosis of PCOS was higher(86.00%),and the value of AMH combined with sex hormones was higher than that of single detection.Conclusion Serum AMH is significant in the diagnosis of polycystic ovary syndrome,and it is more valuable after combined with sex hormone test.
作者
黄倩
尚钊源
宗珂璠
HUANG Qian;SHANG Zhao-yuan;ZONG Ke-fan(Department of Nuclear Medicine,Xuchang 461000,Henan Province,China)
出处
《罕少疾病杂志》
2024年第4期72-73,共2页
Journal of Rare and Uncommon Diseases
关键词
AMH
多囊卵巢综合征
性激素
联合检测
AMH
Polycystic Ovary Syndrome
Sex Hormone
Combined Detection
