摘要
目的探究增强CT及多参数MRI在局灶自身免疫性胰腺炎和胰腺癌诊断中的应用。方法本研究中以2017年9月至2022年10月收治的78例自身免疫性胰腺炎患者作为研究对象,另选取同期在我院进行诊断并治疗的胰腺癌患者78例作为对照组,所有患者入组后,均对患者开展增强CT以及多参数MRI扫描。比较两组患者的影像学特征、各期病灶CT值、ADC、SI指标之间的差异。研究ADC、SI以及CT值的联合诊断对自身免疫性胰腺炎患者的诊断效能。结果研究组以及对照组的胰腺形态异常、胰胆管情况之间的差异存在统计学意义(P<0.05);研究组患者的平扫(t=13.550,P=0.000)、动脉期(t=26.901,P=0.000)、静脉期(t=14.218,P=0.000)以及延迟期(t=107.204,P=0.000)的CT值显著高于对照组,研究组患者的ADC值(t=13.021,P=0.000)、SI(t=13.120,P=0.000)显著低于对照组;ADC、SI以及CT值对于自身免疫性胰腺炎患者的联合诊断的灵敏度显著高于单独检测;通过ROC曲线分析,ADC、SI以及CT值对于自身免疫性胰腺炎患者的联合诊断的曲线下面积显著高于单独检测。结论增强CT各期病灶CT值结合多参数MRI影像特征在局灶性自身免疫性胰腺炎和胰腺癌诊断中具有较强的鉴别诊断意义,建议临床推广。
Objective To explore the application of enhanced CT and multi-parameter MRI in the diagnosis of focal autoimmune pancreatitis and pancreatic cancer.Methods In this study,78 patients with autoimmune pancreatitis admitted from September 2017 to October 2022 were selected as research objects,and 78 patients with pancreatic cancer who were diagnosed and treated in our hospital during the same period were selected as control group.After inclusion,enhanced CT and multi-parameter MRI scans were performed on all patients.The differences in imaging features,CT values,ADC and SI indexes of the two groups were compared.To investigate the diagnostic efficacy of combined ADC,SI and CT values in patients with autoimmune pancreatitis.Results There were statistically significant differences between the study group and the control group in pancreatic morphology abnormalities and pancreatobiliary duct conditions(P<0.05).The CT values of plain scan(t=13.550,P=0.000),arterial stage(t=26.901,P=0.000),venous stage(t=14.218,P=0.000)and delayed stage(t=107.204,P=0.000)in the study group were significantly higher than those in the control group.ADC value(t=13.021,P=0.000)and SI(t=13.120,P=0.000)in the study group were significantly lower than those in the control group.The sensitivity of ADC,SI and CT values in the combined diagnosis of patients with autoimmune pancreatitis was significantly higher than that of single detection.According to ROC curve analysis,the area under the curve of ADC,SI and CT values for the combined diagnosis of patients with autoimmune pancreatitis was significantly higher than that of single detection.Conclusion Enhanced CT value of each phase of the focus combined with multi-parameter MRI image features has a strong differential diagnosis significance in the diagnosis of focal autoimmune pancreatitis and pancreatic cancer,suggesting clinical application.
作者
吴振虎
姚雷
崔碧
李海斌
丁建峰
WU Zhen-hu;YAO Lei;CUI Bi;LI Hai-bin;DING Jian-feng(Imaging Department of Shanxi Yuncheng Central Hospital,Yuncheng 044000,Shanxi Province,China)
出处
《中国CT和MRI杂志》
2024年第4期100-102,共3页
Chinese Journal of CT and MRI
基金
山西省科协建卡科普课题项目(JKKP202115)。
