摘要
目的分析支气管肺泡灌洗液(BALF)在诊断下呼吸道感染中的价值。方法选取2019年6月—2023年6月收治于本院的100例疑似下呼吸道感染患者,分别进行痰病原菌培养、纤维支气管镜防污染毛刷(PSB)刷出物培养与BALF(电子支气管镜采样)培养,回顾性分析培养结果,就3种标本的诊断符合率进行比较,并探讨检测结果的一致性;围绕BALF,分析其病原菌的分布情况及耐药性特点。结果支气管BALF培养诊断符合率最高,PSB刷出物其次。BALF与PSB刷出物的检测结果的一致性非常满意,与痰培养的一致性为比较满意。经BALF培养,共得到89株致病菌,其中,54株革兰阴性杆菌,对抗菌药物有着比较高的耐药性;10株革兰阳性球菌,其耐药性存在两极分化的情况;25株酵母样真菌,其对许多抗真菌药均敏感。结论在对下呼吸道感染进行诊断时,支气管BALF能够诊断符合率高,可明晰病原菌分布及耐药情况。
Objective To analyze the value of bronchoalveolar lavage fluid(BALF)in the diagnosis of lower respiratory tract infection.Methods One hundred patients with suspected lower respiratory tract infections admitted to our hospital from June 2019 to June 2023 were selected for sputum pathogenic bacteria culture,fiberoptic bronchoscopy anti-pollution brush(PSB)brush-out culture and BALF(electronic bronchoscopy sampling)culture,and the culture results were retrospectively analyzed.Comparisons were made regarding the diagnostic compliance rates of the three specimens and the consistency of the test results were explored;the distribution of pathogenic bacteria and drug resistance characteristics were analyzed around BALF.Results Bronchial BALF culture had the highest diagnostic compliance,followed by PSB brush-outs.The agreement between the results of BALF and PSB brush-outs was very satisfactory,and the agreement with sputum cultures was comparatively satisfactory.A total of 89 strains of pathogenic bacteria were obtained by BALF culture,among which,54 strains of gram-negative bacilli,which had a relatively high resistance to antimicrobials;10 strains of gram-positive cocci,which had polarized resistance;and 25 strains of yeast-like fungi,which were susceptible to a wide range of antifungal agents.Conclusions In the diagnosis of lower respiratory tract infections,bronchial BALF enables a high diagnostic compliance rate and clarifies the distribution of pathogenic bacteria and resistance to drugs.
作者
时红菊
蔡向敬
SHI Hongju;CAI Xiangjing(Department of tuberculosis,Liaocheng Infectious Disease Hospital,Liaocheng 252000,China)
出处
《中国医药指南》
2024年第11期76-79,共4页
Guide of China Medicine
关键词
下呼吸道感染
支气管肺泡灌洗液
电子支气管镜
Lower respiratory tract infection
Bronchoalveolar lavage fluid
Electronic bronchoscope
