摘要
目的 分析阴道宫颈环扎术对双胎妊娠宫颈机能不全患者疗效及妊娠结局的影响。方法 选取90例使用辅助生殖技术(ART)的双胎妊娠宫颈机能不全患者,将患者出生日期作为分组基础,应用随机数字分组模式分为观察组和对照组,每组45例。对照组采用传统保胎治疗模式干预,观察组采用阴道宫颈环扎术治疗模式干预。对比两组分娩孕周、实际延长时间、新生儿出生体质量、新生儿Apgar评分、新生儿不良预后情况及不良妊娠结局发生率。结果 对照组分娩孕周为(34.09±2.17)周,实际延长时间为(36.47±3.71)d;观察组分娩孕周为(37.50±1.93)周,实际延长时间为(39.12±2.99)d。观察组分娩孕周、实际延长时间均长于对照组(P<0.05)。对照组新生儿出生体质量为(2231.61±361.60)g,新生儿Apgar评分为(7.91±0.62)分;观察组新生儿出生体质量为(2921.59±861.22)g,新生儿Apgar评分为(8.94±0.84)分。观察组新生儿出生体质量、新生儿Apgar评分大于对照组(P<0.05)。对照组新生儿出现呼吸窘迫综合征7例、缺氧缺血性脑病4例、死亡0例,观察组新生儿出现呼吸窘迫综合征1例、缺氧缺血性脑病0例、死亡0例。观察组新生儿不良预后发生率1.11%低于对照组的12.22%(P<0.05)。两组不良妊娠结局发生率比较无明显差异(P>0.05)。结论 在对ART的双胎妊娠宫颈机能不全患者治疗过程中,灵活地将阴道宫颈环扎术应用于实际治疗中,能够取得更为确切的治疗效果,在保障患者自身安全及预后的情况下,最大程度地改善新生儿的状态,可在今后的治疗中将此类方式推广并加以应用,进而保障患者健康。
Objective To analyze the impact of vaginal cervical cerclage on efficacy and pregnancy outcomes of patients with cervical incompetence in twin pregnancies.Methods A total of 90 patients with cervical incompetence in twin pregnancies with assisted reproductive technology(ART)were selected.Taking the date of birth of the patients as the basis for grouping,they were divided into a control group and an observation group using the random number grouping model.The control group used the traditional fetal preservation treatment model for intervention;The observation group used the vaginal cervical cerclage treatment model for intervention.The gestational age of delivery,actual extension of time,neonatal birth weight,neonatal Apgar score,neonatal adverse prognosis,and incidence of adverse pregnancy outcomes were compared between the two groups.Results In the control group,the gestational week of delivery was(34.09±2.17)weeks and the actual extension of time was(36.47±3.71)d;in the observation group,the gestational week of delivery was(37.50±1.93)weeks,and the actual length of time was(39.12±2.99)d.The gestational week of delivery and actual extension of time in the observation group were longer than those in the control group(P<0.05).In the control group,the neonatal birth weight was(2231.61±361.60)g,and the neonatal Apgar score was(7.91±0.62)points;in the observation group,the neonatal birth weight was(2921.59±861.22)g,and the neonatal Apgar score was(8.94±0.84)points.The neonatal birth weight and neonatal Apgar score in the observation group were higher than those in the control group(P<0.05).Neonates in the control group had 7 cases of respiratory distress syndrome,4 cases of hypoxic ischemic encephalopathy and 0 case of death;neonates in the observation group had 1 case of respiratory distress syndrome,0 case of hypoxic ischemic encephalopathy and 0 case of death.The incidence of adverse neonatal prognosis in the observation group was 1.11%lower than 12.22%in the control group(P<0.05).There was no significant difference in the incidence of adverse pregnancy outcomes between the two groups(P>0.05).Conclusion In the process of treating patients with cervical incompetence in twin pregnancies with ART,flexible application of vaginal cervical cerclage therapy to the actual treatment process can achieve more accurate treatment effects,and improve the state of neonates to the greatest extent under the condition of ensuring the safety and prognosis of patients.
作者
刘津
王义
冷宗祥
LIU Jin;WANG Yi;LENG Zong-xiang(Jilin Provincial Maternal and Child Health Hospital(Jilin Provincial Obstetrics Quality Control Center),Changchun 130000,China)
出处
《中国实用医药》
2024年第6期20-24,共5页
China Practical Medicine
关键词
阴道宫颈环扎术
双胎妊娠宫颈机能不全
分娩孕周
妊娠结局
Vaginal cervical cerclage
Cervical incompetence in twin pregnancies
Gestational age of delivery
Pregnancy outcomes