摘要
中医证候疗效是中医特有且最能体现中医药优势的疗效评价指标。证候疗效评价方法的构建和测量工具的研发,为中医药临床疗效评价与中药新药研发提供客观、量化的证据,是中医药疗效评价创新方法与技术的探索方向。传统中医证候疗效评价的内涵局限于症状、体征的改善,主观因素较强,统一的科学评价标准难以形成,评价方法缺乏统一性和客观性,缺少定量研究。证候疗效的科学内涵、评价思路与方法、关键技术尚不明确,导致中医证候疗效评价模式与方法多样,评价指标各不相同。量表法为中医证候的客观量化和标准化研究提供新思路,成为中医证候疗效评价的重要方法和载体。该文对中医证候疗效评价方法和存在的问题进行系统总结,梳理了中医证候疗效评价量表的研究现状,提出对证候疗效特色与临床价值综合评价的思考,以期为证候疗效评价研究带来更多启示。
Traditional Chinese medicine(TCM)syndrome⁃based efficacy is an evaluation index which is unique to TCM and can reflect the advantages of TCM.The development of the methods and measurement tools for evaluating TCM syndrome⁃based efficacy can provide objective and quantitative evidence for the clinical efficacy evaluation of TCM and the development of new Chinese medicine preparations,being the exploration direction of innovative methods and technologies for evaluating TCM efficacy.The conventional evaluation methods are subjective and limited to the mitigation of symptoms and the improvement of physical signs,which make it difficult to form a unified evaluation standard.In addition,the evaluation methods lack unity,objectivity,and quantitative research.The scientific connotation,evaluation ideas and methods,and key technologies of the evaluation for the therapeutic effect on syndromes remain unclear,which leads to diverse evaluation modes,methods,and indexes.The syndrome⁃based efficacy scale provides a new idea for the objective quantification and standardization of TCM syndromes.This review systematically summarizes the methods and problems,introduces the research progress in the evaluation scales,and puts forward some thoughts on the characteristics of TCM syndrome⁃based efficacy evaluation,aiming to provide insights for the research in this field.
作者
王建新
任毅铭
丰雪
吕行
史琪
郭曼萍
孙明月
高蕊
WANG Jian-xin;REN Yi-ming;FENG Xue;LYU Xing;SHI Qi;GUO Man-ping;SUN Ming-yue;GAO Rui(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China;Center for Post-doctoral Studies,China Academy of Chinese Medical Sciences,Beijing 100700,China;NMPA Key Laboratory for Clinical Research and Evaluation of Traditional Chinese Medicine,Beijing 100091,China;Beijing University of Chinese Medicine,Beijing 100105,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2024年第6期1467-1473,共7页
China Journal of Chinese Materia Medica
基金
中华中医药学会《中医证候疗效评价技术规范》项目(20230145⁃B2⁃CACM)
中国中医科学院科技创新工程重大攻关项目(CI2021A04701)。
关键词
中医证候
疗效评价
量表
traditional Chinese medicine syndrome
efficacy evaluation
scale
