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连续性血液净化治疗重症心力衰竭合并急性肾损伤对患者肾功能、心功能的影响

Effects of Continuous Blood Purification for Severe Heart Failure with Acute Kidney Injury on Patients'Renal and Cardiac Functions
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摘要 目的研究重症心力衰竭伴急性肾损伤患者实施连续性血液净化(Continuous Blood Purification,CBP)治疗的临床效果。方法随机选择2020年1月-2022年6月溧阳市人民医院重症医学科的40例重症心力衰竭合并急性肾损伤患者为研究对象,按照抛硬币法分为对照组和研究组。对照组(20例)予以常规治疗,研究组(20例)予以连续性血液净化治疗。对两组治疗效果、肾功能指标和心功能指标进行对比。结果研究组总疗效(95.00%)较对照组(70.00%)高,差异有统计学意义(χ^(2)=4.329,P=0.037)。研究组血肌酐和血尿素氮水平低于对照组,差异有统计学意义(P均<0.05)。研究组左室射血分数、心排血量高于对照组,差异有统计学意义(P均<0.05)。结论连续血液净化运用于重症心力衰竭并急性肾损伤患者中能提高治疗效果,改善肾功能与心功能。 Objective To study the clinical effect of continuous blood purification(CBP)in patients with severe heart failure and acute kidney injury.Methods 40 patients with severe heart failure and acute kidney injury in the Depart-ment of Critical Care Medicine of Liyang People's Hospital from January 2020 to June 2022 were randomly selected as the study subjects,and were divided into the control group and the study group according to the coin-flip method.The control group(20 cases)was given conventional treatment,and the study group(20 cases)was given continuous blood purification treatment.The treatment effect,renal function indexes and cardiac function indexes of the two groups were compared.Results The total therapeutic effect of the study group(95.00%)was higher than that of the control group(70.00%),and the difference was statistically significant(χ^(2)=4.329,P=0.037).The levels of blood creati-nine and blood urea nitrogen in the study group were lower than those in the control group,and the differences were statistically significant(both P<0.05).The left ventricular ejection fraction and cardiac output in the study group were higher than those in the control group,and the differences were statistically significant(both P<0.05).Conclusion Continuous blood purification used in patients with severe heart failure and acute kidney injury can improve the thera-peutic effect,improve renal function and cardiac function.
作者 张良平 罗志春 胡维 ZHANG Liangping;LUO Zhichun;HU Wei(Department of Critical Care Medicine,Liyang People's Hospital,Changzhou,Jiangsu Province,213300 China)
出处 《中外医疗》 2024年第4期71-74,共4页 China & Foreign Medical Treatment
关键词 重症心力衰竭 连续性血液净化 急性肾损伤 Critical heart failure Continuous blood purification Acute kidney injury
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