摘要
目的:观察手术前给予小儿咪达唑仑对术前焦虑和术后躁动的影响。方法:将2022年1月—2023年1月100例在泉州市第一医院接受手术治疗的患儿纳入研究,依照随机数字表法分为对照组和观察组,各50例。对照组术前30 min口服葡萄糖,观察组术前30 min口服咪达唑仑口服溶液。观察患儿服药前(T_(0))、入室前3 min(T_(1))、麻醉诱导后30 min(T_(2))的生命体征指标[心率(HR)、平均动脉压(MAP)]、术前焦虑情况[改良耶鲁术前焦虑量表(m-YPAS)]、术后躁动情况[小儿麻醉苏醒期躁动(PEAD)量表]及不良反应。结果:观察组T_(1)、T_(2)时的MAP和HR均较T_(0)时均更低,T_(1)时,观察组的MAP、HR均低于对照组,T_(2)时,观察组的MAP、HR均高于对照组,差异均有统计学意义(P<0.05);服药后观察组m-YPAS各项评分均下降,且各项评分均低于对照组,差异均有统计学意义(P<0.05);术后,观察组PEAD各项评分均低于对照组,差异均有统计学意义(P<0.05)。结论:术前给予患儿咪达唑仑可缓解术前焦虑和术后躁动,并能提升麻醉质量,有助于稳定患儿生命体征,并且不增加不良反应发生风险。
Objective:To observe the effect of Midazolam given to children before surgery on preoperative anxiety and postoperative agitation.Method:A total of 100 children who received surgical treatment in Quanzhou First Hospital from January 2022 to January 2023 were included in the study and divided into control group and observation group according to random number table method,with 50 cases in each group.The control group took oral glucose 30 min before surgery,and the observation group took oral Midazolam Oral Solution 30 min before surgery.The vital sign indexes[heart rate(HR),mean arterial pressure(MAP)]before medication(T_(0)),3 min before entering the room(T_(1)),and 30 min after anesthesia induction(T_(2)),preoperative anxiety[modified Yale preoperative anxiety scale(m-YPAS)],postoperative agitation[pediatric anesthesia emergence delirium(PEAD)scale]and adverse reactions in children were observed.Result:MAP and HR in the observation group at T_(1) and T_(2) were lower than those at T_(0),and at T_(1),MAP and HR in the observation group were lower than those in the control group,and at T_(2),MAP and HR in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).After medication,all the scores of m-YPAS in the observation group were decreased,and all the scores were lower than those in the control group,the differences were statistically significant(P<0.05).After surgery,each item score of PEAD in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Midazolam given to children before surgery can alleviate preoperative anxiety and postoperative agitation,improve the quality of anesthesia,help stabilize the vital sign of children,and do not increase the risk of adverse reactions.
作者
刘洋
LIU Yang(Department of Anesthesia,Quanzhou First Hospital,Quanzhou 362000,China)
出处
《中国医学创新》
CAS
2024年第9期138-142,共5页
Medical Innovation of China
关键词
咪达唑仑
小儿手术
术前焦虑
术后躁动
Midazolam
Pediatric surgery
Preoperative anxiety
Postoperative agitation
