摘要
目的:采用数据挖掘技术探寻全国名中医廖志峰治疗失眠的用药规律和用药的临床特点。方法:收集整理近五年(2017—2022年)廖志峰名中医工作室门诊治疗有效的失眠病案,运用Excel 2010、IBM SPSS Statistics 21.0、IBM SPSS Modeler 18.0等软件进行数据统计分析。结果:获得完整的、符合标准的处方共242首,中药177味,其中高频药物有远志(210次)、酸枣仁(164次)、柏子仁(154次)、茯苓(119次)、半夏(115次)、龙骨(115次)等;通过关联规则分析出的相关药物组合中,二项关联规则以“远志→酸枣仁”支持度及置信度排名靠前;三项关联规则以“远志→柏子仁、酸枣仁”支持度及置信度排名靠前。药物关联网络图显示柏子仁、远志、酸枣仁、茯苓、龙骨等药物与其他的高频药物之间关系紧密,用药频率比较高。高频药物可聚为5类。结论:廖志峰名中医辨治失眠用药主要脏腑为心、肝、肾,配伍多在辨证论治的基础上加入安神之品,以四君子汤、酸枣仁汤、天王补心丹、温胆汤等处方为基础方剂,加入镇静安神、宁心安神的药品,处方简练有效,辨证准确。
Objective:To investigate the medication rules and clinical characteristics of the medication used in the treatment of insomnia by national famous TCM doctor Liao Zhifeng using data mining technology.Methods:Excel 2010,IBM SPSS Statistics 21.0 and IBM SPSS Modeler 18.0 and other softwares were applied to perform statistical analysis of data after collecting and sorting the proven cases of treating insomnia in famous doctor Liao Zhifeng′s work studio in the recent five years(from 2017 to 2022).Results:All 242 complete prescriptions met the criterion were obtained,including 177 traditional Chinese medicines,among them,high-frequency drugs contained Yuanzhi(Polygala tenuifolia,210 times),Suanzaoren(Jujube seed,164 times),Baiziren(platycladi semen,154 times),Fuling(poria,119 times),Banxia(pinelliae rhizoma,115 times)and fossil fragments(115 times);among the drug combinations analyzed by association rules,binomial association rules"Yuanzhi-Suanzaoren",and three association rules"Yuanzhi-Baiziren and Suanzaoren"ranked the highest in terms of support and confidence level.The drug association network diagram showed a strong relationship between drugs such as Baiziren,Yuanzhi,Suanzaoren,Fuling and fossil fragments,and other high-frequency drugs,with a relatively high frequency of medication use.High-frequency drugs can be grouped into five categories.Conclusion:Famous doctor Liao Zhifeng considers that the main organs are heart,liver and kidney in his syndrome differentiation and treatment for insomnia,he usually adds the drugs for calming the mind,adopting Sijunzi Tang,Suanzaoren Tang,Tianwang Buxin pills and Wendan Tang as the basic prescriptions,plus sedatives and the medicine of calming the mind,heart and spirit,the prescription is concise and effective with accurate syndrome differentiation.
作者
张丽娜
张参军
何金丽
陶富军
ZHANG Lina;ZHANG Canjun;HE Jinli;TAO Fujun(Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China;Qilihe District People′s Hospital of Lanzhou,Lanzhou 730050,China)
出处
《西部中医药》
2024年第4期53-57,共5页
Western Journal of Traditional Chinese Medicine
基金
国家中医药管理局第四届国医大师传承工作室和第二届全国名中医传承工作室建设项目(国中医药办人教函[2022]245号)
2020年兰州市科技发展指导性计划项目(2020-ZD-33)。
关键词
数据挖掘
失眠
用药规律
名中医经验
廖志峰
data mining
insomnia
medication rule
famous TCM doctors'experience
Liao Zhifeng
