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血清miR-200c-3p结合PA表达水平对重症肺炎儿童预后的评估价值

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摘要 目的 探讨血清miR-200c-3p结合血清前白蛋白(PA)表达水平对重症肺炎(SP)儿童预后的评估价值。方法 选取在本院住院治疗的86例SP儿童,根据其预后情况分为预后良好组(n=68)和预后不良组(n=18)。收集两组患儿的一般资料,记录患儿血清miR-200c-3p及PA的表达情况,ROC曲线分析血清miR-200c-3p结合PA表达水平对SP患儿预后的评估价值。结果 两组患儿年龄、病程及有先天性心脏病和营养不良方面比较差异有统计学意义(P<0.05)。预后良好组血清miR-200c-3p、降钙素原(PCT)及C-反应蛋白(CRP)水平均低于预后不良组,血清PA表达水平高于预后不良组(P<0.05)。ROC曲线分析显示,血清miR-200c-3p、PA及联合检测预测SP患儿预后不良的曲线下面积分别为0.647、0.625、0.754(P<0.05)。结论 血清miR-200c-3p结合PA表达水平对SP儿童预后有较高的评估价值。
机构地区 信阳市中心医院
出处 《实验与检验医学》 CAS 2024年第1期78-81,共4页 Experimental and Laboratory Medicine
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