摘要
目的 探讨双黄连颗粒联合阿奇霉素治疗小儿支原体肺炎的临床效果。方法 选取2020年1月至2022年12月于三原县医院就诊的70例支原体肺炎患儿作为研究对象,按照随机数字表法分为对照组(35例)和观察组(35例)。对照组单用阿奇霉素,观察组在对照组基础上联用双黄连颗粒。比较两组炎症因子水平及临床症状评分。结果 治疗后,两组C反应蛋白、白细胞介素-17、降钙素原和肿瘤坏死因子-α水平均低于治疗前,且观察组低于对照组(P<0.05)。治疗后,两组咳嗽、食欲不振、喘憋、发热评分均低于治疗前,且观察组低于对照组(P <0.05)。结论 双黄连颗粒联合阿奇霉素治疗小儿支原体肺炎的临床效果较好,可有效降低炎症因子水平,减轻患儿临床症状,值得推广。
Objective To investigate the clinical effect of Shuanghuanglian Granules combined with Azithromycin in the treatment of children with Mycoplasma pneumonia.Methods A total of 70 children with Mycoplasma pneumonia who were treated in Sanyuan County Hospital from January 2020 to December 2022 were selected as the research objects.According to the random number table method,they were divided into the control group(35 cases) and the observation group(35 cases).The control group was treated with Azithromycin alone,and the observation group was treated with Shuanghuanglian Granules based on the control group.The levels of inflammatory factors and clinical symptom scores were compared between the two groups.Results After treatment,the levels of C-reactive protein,interleukin-17,procalcitonin and tumor necrosis factor-α in both groups were lower than those before treatment,and those in the observation group were lower than those in the control group(P < 0.05).After treatment,the scores of cough,loss of appetite,dyspnea and fever in both groups were lower than those before treatment,and those in the observation group were lower than those in the control group(P < 0.05).Conclusion Shuanghuanglian Granules combined with Azithromycin has good clinical effect in the treatment of Mycoplasma pneumonia in children,which can effectively reduce the levels of inflammatory factors and alleviate the clinical symptoms of children.
作者
洪妮妮
周凯
HONG Nini;ZHOU Kai(Department of Pediatrics,Sanyuan County Hospital,Shaanxi Province,Sanyuan 713800,China)
出处
《妇儿健康导刊》
2024年第7期66-69,共4页
JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
关键词
双黄连颗粒
阿奇霉素
小儿支原体肺炎
Shuanghuanglian Granules
Azithromycin
Children with Mycoplasma pneumonia
