摘要
目的探讨宫腔镜下冷刀分离术联合COOK球囊治疗宫腔粘连(IUA)患者的临床效果。方法84例IUA患者随机分为两组,对照组采用宫腔镜下冷刀分离术治疗,观察组采用宫腔镜下冷刀分离术联合COOK球囊治疗,比较两组的炎性因子水平、宫腔再次粘连发生率。结果观察组术后1个月的血清IL-4、IL-6、IL-8水平均显著低于对照组(P<0.05)。随访期间,观察组的宫腔再次粘连发生率为4.76%,显著低于对照组的19.05%(P<0.05)。结论宫腔镜下冷刀分离术联合COOK球囊治疗IUA患者能够明显减轻其炎性反应,降低宫腔再次粘连发生率。
Objective To explore the clinical effect of hysteroscopic cold knife separation combined with COOK balloon in the treatment of patients with intrauterine adhesion(IUA).Methods 84 patients with IUA were randomly divided into two groups.The control group was treated with hysteroscopic cold knife separation,and the observation group was treated with hysteroscopic cold knife separation combined with COOK balloon.The levels of inflammatory factors and the incidence of intrauterine re-adhesion were compared between the two groups.Results The levels of serum IL-4,IL-6 and IL-8 at 1 month after surgery in the observation group were significantly lower than those in the control group(P<0.05).During the follow-up period,the incidence of intrauterine re-adhesion in the observation group was 4.76%,significantly lower than 19.05%in the control group(P<0.05).Conclusions Hysteroscopic cold knife separation combined with COOK balloon in the treatment of IUA patients can obviously relieve the inflammatory reaction and reduce the incidence of intrauterine re-adhesion.
作者
张琳
史中娜
ZHANG Lin;SHI Zhongna(Department of Obstetrics and Gynecology,the Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)
出处
《临床医学工程》
2024年第4期415-416,共2页
Clinical Medicine & Engineering
关键词
宫腔粘连
宫腔镜下冷刀分离术
COOK球囊
炎性因子
Intrauterine adhesion
Hysteroscopic cold knife separation
COOK balloon
Inflammatory factor
