摘要
目的:探讨Ⅲ期原发性肝癌中医证候特点。方法:制定“原发性肝癌中医证候分布调查表”,收集739例Ⅲ期原发性肝癌患者的流行病学及中医四诊信息资料,对患者的流行病学资料进行描述性分析,对症状及体征进行因子分析及聚类分析。结果:Ⅲ期原发性肝癌涉及的病位有肝、脾、肾、胆、胃;病性包括气虚、阴虚、阳虚、热、湿、瘀血、气滞;提取11个公共因子,聚为4类时,症状指标分散性良好,证型分布清晰。结论:Ⅲ期原发性肝癌以中老年男性发病率较高,容易出现肝外转移;中医病位主要在肝、脾、胆、肾、胃,病性为本虚标实、虚实夹杂;证候可分为4个证型,肝肾阴虚证,肝郁脾虚证,脾虚湿困证,肝胆湿热、瘀血阻络证。
Objective:Exploring the characteristics of Traditional Chinese Medicine syndrome distribution in PhaseⅢprimary liver cancer.Methods:The epidemiologic and Traditional Chinese Medicine(TCM)informational data pertaining to 739 patients diagnosed with StageⅢprimary hepatic carcinoma were amassed via the"Primary Liver Cancer TCM Syndrome Distribution Questionnaire".An analytical descriptive approach was harnessed to scrutinize the patients'epidemiological data,whereas their symptoms and manifestations were examined through factorial analysis and cluster analysis.Results:StageⅢprimary liver cancer involved liver,spleen,kidney,gallbladder and stomach.Diseases include:qi deficiency,yin deficiency,yang deficiency,heat,dampness,blood stasis and qi stagnation;When 11 common factors were extracted and grouped into 4 categories,the symptom indexes were well dispersed and the syndrome types were clearly distributed.Conclusion:The incidence of stageⅢprimary liver cancer is higher in middle-aged and elderly men,and it is easy to have extrahepatic metastasis.TCM diseases are mainly located in liver,spleen,gallbladder,kidney and stomach.and The disease is based on deficiency and excess,and the deficiency and excess are mixed.Syndrome can be divided into four syndrome types,include liver and kidney yin deficiency syndrome,liver stagnation and spleen deficiency syndrome,syndrome of spleen deficiency and dampness,syndrome of damp-heat in liver and gallbladder,blood stasis blocking collaterals.
作者
李梅
陈新瑜
黄祎
谭梅傲
刘华宝
LI Mei;CHEN Xin-yu;HUANG Yi;LIU Hua-bao(Hepatology Department of Chongqing Traditonal Chinese Medicine Hospital(Chongqing,400021),China)
出处
《中西医结合肝病杂志》
CAS
2024年第4期301-304,309,共5页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金
重庆市科卫联合中医药科研项目青年人才基金项目(No.2019ZY3197)
全国名中医传承工作室[国中医药人教函(2021)202号,渝财社(2023)43号]
中医药防治肝纤维化传承创新团队[渝中医(2022)33号,渝财社(2023)43号]。
关键词
Ⅲ期原发性肝癌
中医证候
因子分析
聚类分析
StageⅢprimary liver cancer
TCM syndromes
Factor analysis
Cluster analysis
