摘要
目的 探究肺康复联合无创通气对重度慢性阻塞性肺疾病血气、肺功能、运动耐力及生活质量的影响。方法 选取2022年6月—2023年10月北京燕化医院呼吸与危重症医学科收治的稳定期重度慢性阻塞性肺疾病患者80例,采用随机数表法分为观察组40例、对照组40例。观察组实施肺康复联合无创通气治疗,对照组实施无创通气治疗。比较两组患者治疗前后血气指标,肺功能,运动耐力及生活质量指标变化。结果 观察组治疗后动脉二氧化碳分压(38.63±2.01)mmHg低于对照组、动脉血氧分压(73.63±3.85)mmHg高于对照组,差异有统计学意义(t=15.547、9.684,P均<0.05)。观察组治疗后肺功能第1秒钟用力呼吸容积(1.68±0.22)L、最大呼气中期流速(1.69±0.41)L/s、第1秒钟用力呼吸容积/用力肺活量(70.96±4.42)%均高于对照组,差异有统计学意义(t=5.979、5.276、12.501,P均<0.05)。观察组6 min步行距离、慢性阻塞性肺疾病评估测试评分均优于干预前,且优于对照组,差异有统计学意义(P均<0.05)。结论 肺康复联合无创通气治疗效果显著,改善患者肺功能。
Objective To explore the effects of pulmonary rehabilitation combined with non-invasive ventilation on blood gas,lung function,exercise endurance and quality of life in severe chronic obstructive pulmonary disease.Methods Eighty patients with severe chronic obstructive pulmonary disease treated in the stable stage from the department of respiratory and critical care medicine of Beijing Yanhua Hospital from June 2022 to October 2023 were selected,and the patients were divided into observation group(40 cases) and control group(40 cases) by random number table method.The observation group was treated with pulmonary rehabilitation combined with non-invasive ventilation,and the control group was treated with non-invasive ventilation.Blood gas index,lung function,exercise endurance and quality of life index were compared between the two groups before and after treatment.Results After treatment,the arterial carbon dioxide pressure(38.63±2.01) mmHg in the observation group was lower than that in the control group,and the arterial oxygen pressure(73.63±3.85) mmHg was higher than that in the control group,and the differences were statistically significant(t=15.547,9.684,both P<0.05).After treatment,the pulmonary function of the first second of forced breathing volume(1.68±0.22) L,maximum mid-expiratory flow rate(1.69±0.41) L/s,forced breathing volume/forced vital capacity in the first second(70.96±4.42) % in the observation group were higher than those in control group,and the differences were statistically significant(t=5.979,5.276,12.501,all P<0.05).The 6min walking distance and chronic obstructive pulmonary disease evaluation test score in the observation group were better than those before intervention,and better than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Pulmonary rehabilitation combined with non-invasive ventilation has a remarkable effect on lung function.
作者
张於
单敏捷
ZHANG Yu;SHAN Minjie(Department of Respiratory Medicine,Beijing Yanhua Hospital,Beijing,102500 China)
出处
《系统医学》
2024年第4期117-120,共4页
Systems Medicine
关键词
重度慢性阻塞性肺疾病
肺康复
无创通气治疗
血气
肺功能
运动耐力
慢性阻塞性肺疾病评估测试问卷
Severe chronic obstructive pulmonary disease
Pulmonary rehabilitation
Non-invasive ventilation therapy
Blood gas
Lung function
Sports endurance
Chronic obstructive pulmonary disease assessment test questionnaire
