摘要
目的观察健脾祛痰化湿化瘀方联合强化生活方式干预治疗腹型肥胖患者的临床效果及对糖脂代谢的影响。方法选取2021年1月至2023年6月新余市中医院体检中心收治的200例腹型肥胖患者作为研究对象,按就诊顺序分为对照组和观察组各100例。对照组给予强化生活方式干预治疗;观察组在对照组基础上给予健脾祛痰化湿化瘀方联合治疗。对两组患者同时进行为期3个月的观察,评估两组有效率,并比较腹围(WC)、体重指数(BMI),总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)及糖化血红蛋白(HbA1c)和空腹血糖的变化情况。结果治疗后,观察组总有效率(80.00%)高于对照组(64.00%),差异有统计学意义(P<0.05);治疗后,观察组WC、BMI水平均低于对照组,差异有统计学意义(P<0.05);治疗后,观察组TC、TG、LDL-C、HbA1c、空腹血糖水平均低于对照组,差异有统计学意义(P<0.05)。结论健脾祛痰化湿化瘀方联合强化生活方式干预治疗腹型肥胖患者在临床上治疗效果明显,能降低患者BMI、WC水平,纠正糖脂代谢异常。
Objective To observe the clinical effect of Jianpi Qutan Huashi Huayu Decoction combined with intensive lifestyle intervention in the treatment of patients with abdominal obesity,and the impact on glucose and lipid metabolism.Methods A total of 200 patients with abdominal obesity who were admitted to Xinyu Hospital of Traditional Chinese Medicine from January 2021 to June 2023were selected as the study objects.They were divided into a control group and an observation group according to the order of treatment,with 100 cases in each group.The control group was given intensive lifestyle intervention.On this basis,the observation group was treated with Jianpi Qutan Huashi Huayu Decoction.The two groups of patients were followed up for 3 months,and the effective rate was evaluated.Changes in waist circumference(WC),body mass index(BMI),total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),glycosylated hemoglobin(HbA1c)and fasting blood glucose were compared between the two groups.Results After treatment,the total effective rate in the observation group was 80.00%,higher than 64.00%in the control group,and the difference was statistically significant(P<0.05).After treatment,WC and BMI in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of TC,TG,LDL-C,HbA1c and fasting blood glucose in the observation group were lower than those in control group,and the differences were statistically significant(P<0.05).Conclusion Jianpi Qutan Huashi Huayu Decoction combined with intensive lifestyle interventionis effective in the treatment of abdominal obesity,which can decrease BMI and WC,and correct abnormal glucose and lipid metabolism.
作者
黄伟珍
彭娟
吴春玉
HUANG Weizhen;PENG Juan;WU Chunyu(Department of Blood Transfusion,Xinyu Hospital of Traditional Chinese Medicine,Jiangxi Province,Xinyu338025,China)
出处
《中国当代医药》
CAS
2024年第11期97-100,共4页
China Modern Medicine
关键词
健脾祛痰化湿化瘀方
强化生活方式干预
腹型肥胖
临床疗效
糖脂代谢
Jianpi Qutan Huashi Huayu Decoction
Intensive lifestyle intervention
Abdominal obesity
Clinical effect
Glucose and lipid metabolism
