摘要
目的探讨消化道早期癌及癌前病变患者给予内镜下黏膜剥离术治疗的效果。方法回顾性选取2021年1—12月龙岩市第二医院消化内科接受手术治疗的102例消化道早期癌及癌前病变患者的临床资料,按照临床手术干预方法分为两组,每组51例。对照组采取内镜下黏膜切除术治疗,观察组采取内镜下黏膜剥离术治疗。比较两组患者的手术切除情况、手术指标、并发症发生率和生活质量评分。结果治疗后,观察组的治愈性切除率为84.31%,整块切除率为96.08%,完整切除率为92.16%,均高于对照组的62.75%、78.43%、74.51%,差异有统计学意义(χ^(2)=6.095、7.141、5.718,P均<0.05)。观察组的近期、远期并发症发生率均低于对照组,差异有统计学意义(P均<0.05)。观察组术后3、6、12个月的生活质量评分均高于对照组,差异有统计学意义(P均<0.05)。结论采取内镜下黏膜剥离手术治疗能够提高切除效果,降低并发症发生率,提高患者的生活质量。
Objective To investigate the effect of endoscopic mucosal dissection in patients with early gastrointestinal cancer and precancerous lesions.Methods The clinical data of 102 patients with early gastrointestinal cancer and pre-cancerous lesions who received surgical treatment in the gastroenterology Department of the Second Hospital of Long-yan City from January to December 2021 were retrospectively selected and divided into two groups according to clini-cal surgical intervention methods,with 51 cases in each group.The control group was treated with endoscopic mucosal resection,and the observation group was treated with endoscopic mucosal dissection.The surgical resection,surgical indexes,the incidence of complications and quality of life scores were compared between the two groups of patients.Results After treatment,the curative resection rate of the observation group was 84.31%,the whole resection rate was 96.08%,and the complete resection rate was 92.16%,which were higher than 62.75%,78.43%,74.51%of the control group,and the differences were statistically significant(χ^(2)=6.095,7.141,5.718,all P<0.05).The incidence of short-term and long-term complications in the observation group were lower than that in the control group,and the differ-ences were statistically significant(both P<0.05).The life quality scores of the observation group at 3,6 and 12 months after operation were higher than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion Endoscopic mucosal dissection can improve the resection effect,reduce the incidence of compli-cations and improve patients'quality of life.
作者
章杰
ZHANG Jie(Department of Gastroenterology,Longyan Second Hospital,Longyan,Fujian Province,364000 China)
出处
《中外医疗》
2024年第6期57-61,共5页
China & Foreign Medical Treatment
关键词
消化道早期癌
癌前病变
黏膜剥离术
临床效果
Early gastrointestinal cancer
Precancerous lesions
Mucosal resection
Clinical effect
