摘要
目的:探讨项痹通颗粒联合颈部力量康复训练治疗风寒湿型颈型颈椎病的疗效。方法:200例患者随机分为对照组及观察组各100例。观察组干预措施为颈部力量康复训练联合口服项痹通颗粒;对照组干预措施为米字操锻炼联合口服塞来昔布,7 d为1个疗程,共治疗2个疗程。观察两组患者治疗前后视觉模拟评分(VAS)、颈部残障指数(NDI)、椎动脉(VA)和基底动脉(BA)血流速度及血清中炎症小体(NLRP3)和促炎因子白细胞介素-1β(IL-1β)水平的变化,并将结果进行统计学分析。结果:两组各观察指标在治疗前相比均无统计学意义(P>0.05)。治疗后,两组VAS、NDI、NLRP3及IL-1β水平均降低,且观察组低于对照组(P<0.05);两组患者VA和BA的血流速度均提升,且观察组高于对照组(P<0.05);观察组治疗后的综合疗效优于对照组(P<0.05)。结论:项痹通颗粒联合颈部力量康复训练治疗风寒湿型颈型颈椎病临床疗效显著。
Objective:To explore the curative effect of Xiangbitong granule combined with neck strength rehabilitation training on wind-colddampness type cervical spondylosis.Methods:200 patients were randomly divided into control group and observation group with 100 cases each.The intervention measures of the observation group were neck strength rehabilitation training combined with oral Xiangbitong granules.The intervention measures of the control group were rice word exercise combined with oral celecoxib,7 days for 1 course of treatment,a total of 2 courses of treatment.VAS,NDI,VA and BA before and after treatment were observed in the two groups.BA blood flow velocity and serum inflammatory body NLRP3 and proinflammatory factor IL-1β levels were statistically analyzed.Results:There was no significant difference between the two groups before treatment(P>0.05).After treatment,VAS,NDI,NLRP3 and IL-1β levels in both groups were decreased,and observation group was lower than control group(P<0.05).The blood flow velocity of VA and BA in both groups was increased,and the observation group was higher than the control group(P<0.05).The comprehensive curative effect of observation group was better than that of control group(P<0.05).Conclusion:Xiangbitong granule combined with neck strength rehabilitation training has significant clinical effect on wind-cold-dampness type cervical spondylosis.
作者
陈敬伟
苏美意
刘琨
张炎明
杨淑荃
欧志文
范德辉
CHEN Jing-wei;SU Mei-yi;LIU Kun;ZHANG Yan-ming;Yang Shu-quan;OU Zhi-Wen;FAN De-hui(The Second Hospital of Traditional Chinese Medicine of Guangdong Province,Guangzhou 510095,China;Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,China)
出处
《中医康复》
2024年第6期52-56,共5页
Traditional Chinese Medicine Rehabilitation
基金
广东省中医药局中医药专项研究课题(20213002)
广东省科技厅区域联合基金-青年基金项目(2021A1515110736)
广东省中医药研究开发重点实验室面上项目课题(KFKT01-001)。
