摘要
目的 探讨重症监护病房颅脑损伤患者发生肠内营养相关性腹泻的影响因素。方法 选取经鼻胃管途径行肠内营养治疗的124例重型颅脑损伤患者为研究对象,观察肠内营养后7 d内的腹泻发生情况,采用Logistic回归模型分析患者发生肠内营养相关性腹泻的危险因素。结果 124例重型颅脑损伤患者肠内营养期间发生腹泻41例,发生率为33.06%;Logistic回归分析显示:GCS评分<5分(OR=3.155)、营养剂日用量≥1 000 mL/d(OR=1.293)、低蛋白血症(OR=4.018)、使用抗生素≥2种(OR=2.161)、经消化道使用钾制剂(OR=2.902)、禁食时间>48 h(OR=2.730)是重型颅脑损伤患者发生肠内营养相关性腹泻的危险因素(P<0.05)。结论 GCS评分、营养剂用量、禁食时间,以及使用抗生素、钾制剂情况,与重型颅脑损伤患者发生肠内营养相关性腹泻有关。
Objective To investigate the incidence and influencing factors of enteral nutrition related diarrhea in patients with severe traumatic brain injury in the intensive care unit.Methods A total of 124 patients with severe traumatic brain injury undergoing enteral nutrition therapy through a nasogastric tube were selected to observe the occurrence of diarrhea within 7 d after enteral nutrition.Logistic regression analysis was conducted to identify the risk factors for enteral nutrition-related diarrhea in these patients.Results Among the 124 patients with severe traumatic brain injury,41 cases experienced diarrhea during enteral nutrition,resulting in an incidence rate of 33.06%.Logistic regression analysis revealed that the following factors were significantly associated with an increased risk of enteral nutrition-related diarrhea in patients with severe traumatic brain injury(P<0.05):Glasgow coma scale(GCS) score<5(OR=3.155),daily dosage of nutritional supplements≥1 000 mL/d(OR=1.293),hypoalbuminemia(OR=4.018),use of two or more antibiotics(OR=2.161),use of potassium preparations via the digestive tract(OR=2.902),and fasting for more than 48 hours(OR=2.730).Conclusions The occurrence of enteral nutrition-related diarrhea in patients with severe traumatic brain injury is associated with factors such as GCS score,dosage of nutritional supplements,fasting duration,use of antibiotics,and use of potassium preparations via the digestive tract.
作者
张颖
陈雅芳
徐帅
黄小红
何学愚
ZHANG Ying;CHEN Yafang;XU Shuai;HUANG Xiaohong;HE Xueyu(Emergency Department,Coast Guard Hospital of Chinese People s Armed Police Force,Jiaxing 314000,China)
出处
《健康研究》
CAS
2024年第2期208-212,共5页
Health Research
关键词
重型颅脑损伤
腹泻
肠内营养
危险因素
severe traumatic brain injury
diarrhea
enteral nutrition
risk factor
