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UPPP手术对OSA患者觉醒阈值影响的研究

Impact of UPPP surgery on the arousal threshold in patients with OSA
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摘要 目的 讨论悬雍垂腭咽成形(UPPP)手术对阻塞性睡眠呼吸暂停(OSA)患者觉醒阈值的影响。方法 选取2017年2月~2018年6月期间因OSA于本院耳鼻喉科完善双侧扁桃体切除+UPPP手术的患者,分析并对比其术前、术后的多导睡眠指标及觉醒阈值的差异。结果 UPPP术可以显著改善重度OSA患者的呼吸暂停指数(AHI)及夜间最低血氧饱和度。重度OSA患者的觉醒阈值高于轻-中度OSA患者,UPPP术后重度OSA患者的觉醒阈值较术前显著降低。结论 OSA患者的觉醒阈值随疾病程度加重而上升,UPPP术可以降低重度OSA患者的觉醒阈值。 Objective To assess the impact of uvulopalatopharyngoplasty(UPPP) surgery on the arousal threshold in patients with obstructive sleep apnea(OSA).Methods Data from patients who underwent tonsillectomy and UPPP surgery for OSA at our hospital's department of Otolaryngology between February 2017 and June 2018 were collected.The differences in preoperative and postoperative sleep data as well as arousal threshold were analyzed and compared.Results UPPP significantly improved the apnea-hypopnea index(AHI) and minimum nocturnal oxygen saturation in patients with severe OSA.Patients with severe OSA had higher arousal thresholds compared to those with mild-to-moderate OSA.Following UPPP surgery,the arousal thresholds decreased in patients with severe OSA.Conclusion The severity of OSA is positively correlated with an elevated arousal threshold.UPPP surgery can reduce arousal thresholds in patients with severe OSA.
作者 王钰彧 朱梅 王林娥 WANG Yuyu;ZHU Mei;WANG Line(Department of Otorhinolaryngology,Beijing Friendship Hospital,Affiliated to Capital Medical University,Beijing,100050,China)
出处 《中国中西医结合耳鼻咽喉科杂志》 2024年第2期140-142,135,共4页 Chinese Journal of Otorhinolaryngology in Integrative Medicine
关键词 阻塞性睡眠呼吸暂停 悬雍垂腭咽成形术 觉醒阈值 手术疗效 临床特征 obstructive sleep apnea uvulopalatopharyngoplasty arousal threshold surgical effect clinical features
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