摘要
目的:分析老年冠心病患者经皮冠状动脉介入治疗(PCI)术后发生冠状动脉无复流的影响因素,为临床预防PCI术后冠状动脉无复流的发生提供依据。方法:选择2021年6月—2023年6月首都医科大学石景山教学医院收治的163例行PCI的老年冠心病患者作为研究对象,依照是否存在复流将患者分为无复流组(n=83)和血流正常组(n=80)。比较两组的一般资料及实验室指标,采用logistic回归分析影响老年冠心病患者PCI术后发生冠状动脉无复流的危险因素。结果:两组年龄、饮酒史及家族史比较,差异无统计学意义(P>0.05);无复流组有吸烟史、心绞痛发生史、术前血糖≥11.0 mmol/L及高密度脂蛋白胆固醇(HDL-C)<45 mg/dL患者占比高于血流正常组,差异有统计学意义(P<0.05);logistic分析结果提示,吸烟史及术前血糖≥11.0 mmol/L是老年冠心病患者PCI术后发生冠状动脉无复流发生的危险因素(P<0.05),无心绞痛发生史及HDL-C≥45 mg/dL是老年冠心病患者PCI术后发生冠状动脉无复流发生的保护因素(P<0.05)。结论:有吸烟史及术前血糖≥11.0 mmol/L是PCI术后发生冠状动脉无复流的危险因素,无心绞痛发生史及HDL-C≥45 mg/dL是PCI术后发生冠状动脉无复流的保护因素;冠心病患者应控制血糖血脂,保持健康生活习惯,早日戒烟,发生心绞痛后及时干预治疗。
Objective:To analyze the influencing factors of coronary no-reflow in elderly patients with coronary heart disease after percutaneous coronary intervention(PCI),and to provide a basis for clinical prevention of coronary no-reflow after PCI.Method:A total of 163 elderly patients with coronary heart disease undergoing PCI admitted to Shijingshan Teaching Hospital of Capital Medical University from June 2021 to June 2023 were selected as the study objects.According to the presence or absence of reflow,the patients were divided into no-reflow group(n=83)and normal blood flow group(n=80).The general data and laboratory indicators of the two groups were compared,and the risk factors affecting the occurrence of coronary no reflow in elderly patients with coronary heart disease after PCI were analyzed by logistic regression.Result:There were no significant differences in age,drinking history and family history between the two groups(P>0.05).The proportion of patients with smoking history,angina pectoris history,preoperative blood glucose≥11.0 mmol/L and high-density lipoprotein cholesterol(HDL-C)<45 mg/dL in the no-reflow group were higher than those in the normal blood flow group,the differences were statistically significant(P<0.05).logistic analysis results indicated that smoking history and preoperative blood glucose≥11.0 mmol/L were risk factors for coronary no-reflow after PCI in elderly patients with coronary heart disease(P<0.05).No history of angina pectoris and HDL-C≥45 mg/dL were the protective factors for coronary no-reflow after PCI in elderly patients with coronary heart disease(P<0.05).Conclusion:History of smoking and preoperative blood glucose≥11.0 mmol/L were risk factors for coronary no-reflow after PCI,and no history of angina pectoris and HDL-C≥45 mg/dL were protective factors for coronary no-reflow after PCI.Patients with coronary heart disease should control blood glucose and lipids,maintain a healthy lifestyle,quit smoking as soon as possible,and intervene in time after angina pectoris.
作者
李明昌
LI Mingchang(Shijingshan Teaching Hospital of Capital Medical University,Beijing 100043,China)
出处
《中外医学研究》
2024年第10期111-114,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
老年
冠心病
经皮冠状动脉介入治疗
冠状动脉无复流
危险因素
Elderly
Coronary heart disease
Percutaneous coronary intervention
No-reflow of coronary artery
Risk factors
