摘要
目的探讨超微血流成像技术对新生儿颅脑室管膜下疾病(出血及囊肿)的诊断价值。方法应用超声检查新生儿颅脑,将尾状核头部和丘脑交界处室管膜下出现强回声团或囊性回声标记为阳性指标,将患儿分为三组:正常组、强回声组和囊肿组,分别应用超微血流成像技术观测新生儿尾状核头部和丘脑交界处室管膜区的血流情况,并对病变组(强回声组和囊肿组)进行动态观察以明确诊断并随访。结果观察正常组30例患儿,室管膜下围绕脑室可见星点状及带状血流信号,血流信号丰富程度随侧脑室及脉络丛强回声增多而增丰;强回声组18例,其强回声与脉络丛回声相似,16例(16/18)超微血流成像显示此区域可以见丰富血流信号,其血流信号与脉络丛显示相似,并且其血流在室管膜下与远端脉络丛相连,其中2例(2/18)强回声内部未探及血流信号,后期随访转为囊状回声;囊肿组11例,室管膜下囊肿周边可见丰富血流信号,囊肿周边随强回声团增加其血流显示更丰富,8例(8/17)囊肿内可见血流信号。结论超微血流成像可明确室管膜下区早期病变性质,可以动态观测疾病进展及推测预后,为临床提供更全面的诊断信息,或许此技术的应用将成为室管膜下出血诊断的金标准。
Objective To explore the diagnostic value of ultra micro blood flow imaging in neonatal subependymal diseases(hemorrhage and cyst).Methods Ultrasound was used to examine the newborn's brain,and the strong echo mass or cystic echo under the ependyma at the junction of caudate nucleus and thalamus was marked as a positive indicator.The children were divided into three groups:normal group,strong echo group and cyst group.The blood flow in the ependyma at the junction of caudate nucleus and thalamus was observed by ultra-micro blood flow imaging technology respectively,and the pathological groups(strong echo group and cyst group)were dynamically observed to make a clear diagnosis and follow-up.Results In the normal group,30 children were observed,and dotted and banded blood flow signals could be seen around the ventricle under the ependyma,and the richness of blood flow signals increased with the increase of strong echoes in the lateral ventricle and choroid plexus.There are 18 cases in the strong echo group in this study,and their strong echo is similar to that of choroid plexus.Among them,16 cases(16/18)showed abundant blood flow signals in this area,and the blood flow signals in the strong echo area were similar to those in the choroid plexus,and their blood flow was connected with the distal choroid plexus under the ependyma.Among them,2 cases(2/18)with strong echo did not detect blood flow signal,and later follow-up turned into cystic echo.In this study,there were 11 cases in the cyst group,and there were abundant blood flow signals around the subependymal cyst by ultra-micro blood flow examination,and the blood flow signals around the cyst were more abundant with the increase of strong echo group,among which 8 cases(8/17)were found in the cyst.Conclusion Ultra-micro blood flow imaging can clarify the nature of early lesions in subependymal region,dynamically observe the progress of the disease and predict the prognosis,and provide more comprehensive diagnostic information for clinic.Perhaps the application of this technology will become the gold standard for the diagnosis of subependymal hemorrhage.
作者
何学森
赵颖
涂常清
李志菊
黄晏珊
曾淑娟
凌思卓
HE Xue-sen;ZHAO Yring;TU Chang-qing;LI Zhi-ju;HUANG Yan-shan;ZENG Shu-juan;LING Si-zhuo(Prevention and Health Care Management Office,Longgang Central Hospital,Shenzhen 518116,Guangdong Province,China)
出处
《罕少疾病杂志》
2024年第5期27-29,共3页
Journal of Rare and Uncommon Diseases
基金
广东省深圳市龙岗区科技发展专项资金项目(LGKCYLWS2020015)。
关键词
超微血流成像
超声诊断
血流
新生儿
室管膜下
出血
囊肿
Ultramicro Blood Flow Imaging
Ultrasound Diagnosis
Blood Flow
Newborn
Subependymal
Bleeding
Cyst
