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七氟烷复合瑞芬太尼持续泵注在腹腔镜胆囊切除术中的应用效果研究

Study on the Application Effect of Continuous Infusion of Sevoflurane Combined with Remifentanil in Laparoscopic Cholecystectomy
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摘要 探讨七氟烷复合瑞芬太尼持续泵注在腹腔镜胆囊切除术中的应用效果。选取2021年3月—2023年3月贵州省第三人民医院收治的50例接受腹腔镜胆囊切除术的患者为研究对象,将其随机分为对照组和试验组,每组各25例。对照组患者以丙泊酚联合瑞芬太尼维持麻醉,试验组患者以七氟烷联合瑞芬太尼维持麻醉,比较两种麻醉方式的临床应用效果。结果显示,气管插管即刻、气腹建立3 min后,试验组心率、平均动脉压及血氧饱和度水平较对照组更高(P<0.05);苏醒期,试验组steward评分较对照组更高(P<0.05),意识和自主呼吸恢复时间、拔管时间较对照组更短(P<0.05);气管插管及手术结束时,试验组Ramsay评分较对照组更高(P<0.05);两组患者不良反应发生率无显著差异(P>0.05)。研究发现,在腹腔镜胆囊切除术中应用七氟烷复合瑞芬太尼维持麻醉,可减弱手术对患者血液循环的抑制作用,有利于稳定患者血流动力学指标,镇静效果显著,安全性较高,具有临床应用价值。 Exploring the application effect of continuous infusion of sevoflurane combined with remifentanil in laparoscopic cholecystectomy.Fifty patients who underwent laparoscopic cholecystectomy and were admitted to the Third People’s Hospital of Guizhou Province from March 2021 to March 2023 were selected as the study subjects.They were randomly divided into a control group and an experimental group,with 25 cases in each group.The control group patients were maintained under anes-thesia with propofol combined with remifentanil,while the experimental group patients were maintained under anesthesia with sevoflurane combined with remifentanil.The clinical application effects of the two anesthesia methods were compared.The results showed that immediately after tracheal intubation and 3 minutes after pneumoperitoneum establishment,the heart rate,mean arterial pressure,and blood oxygen saturation levels in the experimental group were higher than those in the control group(P<0.05);During the awakening period,the Steward score of the experimental group was higher than that of the control group(P<0.05),and the recovery time of consciousness and spontaneous breathing,as well as the time to extubate,were shorter than those of the control group(P<0.05);At the end of tracheal intubation and surgery,the Ramsay score in the experimental group was higher than that in the control group(P<0.05);There was no significant difference in the incidence of adverse reactions between the two groups of patients(P>0.05).Research has found that the use of sevoflurane combined with remifentanil to maintain anesthesia during laparoscopic cholecystectomy can weaken the inhibitory effect of surgery on patient blood circulation,help stabilize patient hemodynamic indicators,have significant sedative effects,high safety,and have clinical application value.
作者 王朝丹 Wang Chaodan(The Third People’s Hospital of Guizhou Province,Guiyang,Guizhou 550000)
出处 《科技与健康》 2024年第8期53-56,共4页 Technology and Health
关键词 腹腔镜胆囊切除术 七氟烷 瑞芬太尼 应用效果 laparoscopic cholecystectomy heptafluoroalkane remifentanil application effect
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