摘要
从“二本三枢”理论出发,对慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)合并阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS),即重叠综合征(overlap syndrome,OVS)的病机进行探讨。提出二本不足、本源亏虚是OVS发病的关键病机,枢机不利、气血津液代谢失调是OVS发病的核心病理环节。主张根据COPD缓解期和急性期合并OSAHS的不同特点进行分期论治。缓解期以脾肾本源不足为核心,以补先天,养后天为治疗原则;急性期以痰瘀阻滞气机,肺失宣降为核心,以和枢机,解郁结为治疗原则。
The study discussed the pathogenesis of the chronic obstructive pulmonary disease(COPD)combined with obstructive sleep apnea-hypopnea syndrome(OSAHS)based on the theory of“two bases and three pivots”.COPD combined with OSAHS is also named overlap syndrome(OVS).The deficiency of“two bases”is the core pathogenesis of OVS.The inharmony of“three pivots”and the imbalance of metabolism in qi,blood,and body fluid is the core pathological link of OVS.We advocate staged treatment according to the different characteristics of COPD in remission and acute stage combined with OSAHS.In the remission stage,the core pathogenesis is the deficiency of the spleen and kidney,and the principle of treatment is to nourish the innate and the acquired;in the acute stage,the core pathogenesis is phlegm and blood stasis obstructing ascending and descending of qi,and the principle of treatment is to harmonize principal axis and regulate stagnation and inversion of qi.
作者
刘美苹
曹龙
张心月
何荣
朱雪
邵雨萌
LIU Meiping;CAO Long;ZHANG Xinyue(Shandong University of Traditional Chinese Medicine,Jinan Shandong 250355,China;Rizhao Hospital of Traditional Chinese Medicine,Rizhao Shandong 276800,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan Shandong 250014,China)
出处
《四川中医》
2024年第3期32-37,共6页
Journal of Sichuan of Traditional Chinese Medicine
基金
国家自然科学基金(青年科学基金项目)(编号:81503547)
山东省中医药科技发展计划项目(编号:2019-0125)。
关键词
慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停低通气综合征
二本
三枢
chronic obstructive pulmonary disease combined with obstructive sleep apnea-hypopnea syndrome
two bases
three pivots
