摘要
目的研究镇肝熄风汤以及丁咯地尔联用对椎基底动脉供血不足性眩晕的效果。方法选择2020年1月—2023年1月府谷县中医医院收治的84例椎基底动脉供血不足性眩晕患者,采取随机数表法分为两组。两组均使用镇静、氟桂利嗪和胞二磷胆碱等常规的支持疗法。在此基础上,对照组静脉滴注剂量为0.2 g的丁咯地尔,1次/d;观察组联合服用镇肝熄风汤。比较两组基底动脉以及椎动脉的血管搏动指数、平均血流速度,评估眩晕障碍调查表以及眩晕评估量表评分,检测血液流变学。结果治疗后,两组患者的基底动脉以及椎动脉的血管搏动指数明显降低(P<0.05),平均血流速度明显升高(P<0.05),且观察组基底动脉以及椎动脉的血管搏动指数明显低于对照组(P<0.05),平均血流速度明显高于对照组(P<0.05);治疗后,两组患者的眩晕障碍调查表以及眩晕评估量表评分明显降低(P<0.05),观察组的眩晕障碍调查表以及眩晕评估量表评分明显低于对照组(P<0.05);治疗后,两组患者的纤维蛋白原、血浆黏度、血细胞压积和全血黏度明显降低(P<0.05),观察组的纤维蛋白原、血浆黏度、血细胞压积和全血黏度明显低于对照组(P<0.05)。结论镇肝熄风汤联合丁咯地尔对于椎基底动脉供血不足性眩晕具有较好效果,能明显增加血流速度,降低患者的血液黏度,改善椎基底动脉的血液循环障碍和眩晕症状,恢复脑部的供血,值得临床应用。
Objective To study the effect of Zhengan Xifeng Decoction combined with buflomedil on vertebrobasilar artery insufficiency vertigo.Methods A total of 84 patients with vertebra basilar insufficiency vertigo from January 2020 to January 2023 in Fugu County Hospital of Traditional Chinese Medicine were selected and divided into two groups by random number table method.Both groups were treated with routine supportive therapy such as sedation,flunarizine and citicoline.On this basis,the intravenous infusion dose of 0.2 g buflomedil was given to the control group once a day.The observation group was combined with Zhengan Xifeng Decoction.Compare the vascular pulsatility index,and average blood flow velocity of the basilar and vertebral arteries between the two groups,evaluate the vertigo disorder questionnaire and vertigo assessment scale scores,and detect blood rheology.Results After treatment,the pulse index of the basilar artery and the vertebral artery in the two groups was significantly decreased(P<0.05),and the mean blood flow velocity was significantly increased(P<0.05).Moreover,the pulse index of the basilar artery and the vertebral artery in the observation group was significantly lower than that in the control group(P<0.05),and the mean blood flow velocity was significantly higher(P<0.05).After treatment,the scores of vertigo disorders questionnaire and vertigo assessment scale in the two groups were significantly lower(P<0.05),and the scores of vertigo disorders questionnaire and vertigo assessment scale in the observation group were significantly lower(P<0.05).After treatment,the reduced whole-blood viscosity,plasma viscosity,hematocrit and whole-blood viscosity of the two groups were significantly reduced(P<0.05),while the reduced whole-blood viscosity,plasma viscosity,hematocrit and whole-blood viscosity of the observation group were significantly lower(P<0.05).Conclusion Zhengan Xifeng Decoction combined with bufldil has satisfactory effect on vertebrobasilar artery insufficiency vertigo,which can significantly increase blood flow velocity,reduce blood viscosity of patients,improve blood circulation disorders and vertigo symptoms of vertebrobasilar artery.It's worth application.
作者
杨茜
孙文燕
YANG Xi;SUN Wen-yan(Traditional Chinese Medicine Pharmacy,Fugu County Hospital of Traditional Chinese Medicine,Yulin Shaanxi,719400,China)
出处
《中华养生保健》
2024年第11期33-36,共4页
CHINESE HEALTH CARE
