摘要
目的评估450 nm半导体蓝激光前列腺汽化切除术治疗良性前列腺增生(BPH)的手术疗效及安全性。方法回顾性分析皖南医学院第二附属医院泌尿外科2023年3—11月40例采用450 nm半导体蓝激光前列腺汽化切除术治疗的BPH患者临床资料,比较患者手术前后的最大尿流率(Qmax)、残余尿量(PVR)、国际前列腺症状评分(IPSS)、生活质量评定量表(QoL)评分变化及手术时间、术后膀胱冲洗时间和术后血红蛋白下降值。结果40例患者均顺利完成手术。患者术后1月Qmax明显高于术前[(16.8±2.5)mL/s vs.(7.9±2.1)mL/s,P<0.05],术后PVR明显低于术前[(14.6±11.4)mL vs.(110.0±42.1)mL,P<0.05],术后IPSS[(11.8±4.0)分vs.(25.0±3.1)分,P<0.05]及QoL评分均明显低于术前[(2.5±0.6)分vs.(5.1±0.9)分,P<0.05]。患者手术时间(52.5±15.5)min,术后膀胱冲洗时间(22.3±4.9)h,术后血红蛋白下降值(6.5±3.8)g/L。2例患者拔除尿管后再次予以导尿,1例患者出院后出现血尿。结论450 nm半导体蓝激光前列腺汽化切除术可显著改善BPH患者的临床症状,提高围手术期的安全性,具有汽化效率高、止血效果好等特点,值得在临床推广应用。
Objective To evaluate the safety and efficacy of 450 nm blue laser vaporization prostatectomy in the treatment of benign prostatic hyperplasia(BPH).Methods A retrospective analysis was conducted on 40 BPH patients treated with 450 nm blue laser vaporization prostatectomy at our hospital during Mar.and Nov.2023.The preoperative and postoperative maximum urinary flow rate(Qmax),post-void residual volume(PVR),international prostate symptom score(IPSS),and quality of life(QoL)score were compared.The operation time,postoperative bladder irrigation time,and postoperative hemoglobin decrease were recorded.Results All operations were successful.One month after surgery,the Qmax[(7.9±2.1)mL/s vs.(16.8±2.5)mL/s]was significantly higher,while PVR[(110.0±42.1)mL vs.(14.6±11.4)mL],IPSS[(25.0±3.1)vs.(11.8±4.0)],and QoL[(5.1±0.9)vs.(2.5±0.6)]were significantly lower,with statistical significance(P<0.05).The operation time was(52.5±15.5)min,the bladder irrigation time was(22.3±4.9)h,the postoperative hemoglobin drop was(6.5±3.8)g/L.Urinary retention occurred in 2 patients after removal of the catheter.Gross hematuria occurred in 1 patient after discharge.Conclusion Vaporization prostatectomy with 450 nm blue laser can significantly improve clinical symptoms and perioperative safety,with high vaporization efficiency and good hemostatic effects.It is worthy of clinical promotion and application.
作者
王宇
徐炜
周发友
徐瑞
谢辉
崔强
郭松林
WANG Yu;XU Wei;ZHOU Fayou;XU Rui;XIE Hui;CUI Qiang;GUO Songlin(Department of Urology,The Second Affiliated Hospital of Wannan Medical College,Wuhu 241000,China)
出处
《现代泌尿外科杂志》
CAS
2024年第5期432-434,444,共4页
Journal of Modern Urology
