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股骨近端防旋髓内钉对老年股骨转子间骨折患者骨代谢及骨强度指标的影响

Effects of proximal femoral nail antirotation on bone metabolism and bone strength indexes in elderly patients with intertrochanteric femoral fracture
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摘要 目的 研究股骨近端防旋髓内钉(PFNA)治疗老年股骨转子间骨折的价值。方法 选取2019年1月至2023年7月我院收治的60例老年股骨转子间骨折患者为研究对象,根据随机数字表法将其分为对照组(n=30)和观察组(n=30)。对照组采用动力髋螺钉治疗,观察组采用PFNA治疗。比较两组的治疗效果。结果观察组的手术时间及骨折平均愈合时间均短于对照组,术中出血量少于对照组(P<0.05)。治疗后,观察组的视觉模拟量表(VAS)评分低于对照组,Harris髋关节功能评分(HHS)评分高于对照组(P<0.05)。治疗后,观察组的骨钙素(BGP)、Ⅰ型前胶原N端前肽(PⅠNP)水平高于对照组,Ⅰ型胶原C端肽(CTX-Ⅰ)水平低于对照组(P<0.05)。治疗后,观察组的白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)水平低于对照组(P<0.05)。治疗后,观察组的屈曲比率(BR)低于对照组,横截面转动惯量(CSMI)、骨密度(BMD)高于对照组(P<0.05)。观察组的并发症总发生率低于对照组(P<0.05)。结论 PFNA治疗老年股骨转子间骨折患者效果显著,能改善骨代谢、骨强度指标。 Objective To investigate the value of proximal femoral nail antirotation(PFNA)in the treatment of elderly patients with intertrochanteric femoral fracture.Methods Sixty elderly patients with intertrochanteric femoral fracture admitted in our hospital from January 2019 to July 2023 were selected as the study objects and divided into control group(n=30)and observation group(n=30)according to random number table method.The control group was treated with dynamic hip screw,and the observation group was treated with PFNA.The therapeutic effects of the two groups were compared.Results The operative time and mean healing time of fracture in the observation group were shorter than those in the control group,and the amount of intraoperative blood loss was lower than that in the control group(P<0.05).After treatment,the Visual Analogue Scale(VAS)score of the observation group was lower than that of the control group,and the Harris Hip Score(HHS)score was higher than that of the control group(P<0.05).After treatment,the levels of osteocalcin(BGP)and N-terminal propeptide of typeⅠprocollagen(PⅠNP)in the observation group were higher than those in the control group,and the level of typeⅠcollagen C-terminal peptide(CTX-Ⅰ)was lower than that in the control group(P<0.05).After treatment,the levels of interleukin-6(IL-6),interleukin-1β(IL-1β)and tumor necrosis factor-α(TNF-α)in the observation group were lower than those in the control group(P<0.05).After treatment,the buckling ratio(BR)of the observation group was lower than that of the control group,and the cross-sectional moment of inertia(CSMI)and bone mineral density(BMD)were higher than those of the control group(P<0.05).The total incidence of complications of the observation group was lower than that of the control group(P<0.05).Conclusion PFNA has a significant effect in the treatment of elderly patients with intertrochanteric femoral fracture,which can improce the bone metabolism and bone strength indexes.
作者 陈红伟 吕波 CHEN Hongwei;LYU Bo(Orthopedics Department,Traditional Chinese Medicine Hospital of Bo'ai County,Jiaozuo 454450,China)
出处 《临床医学研究与实践》 2024年第15期92-95,共4页 Clinical Research and Practice
关键词 股骨近端防旋髓内钉 老年患者 股骨转子间骨折 proximal femoral nail antirotation elderly patient intertrochanteric femoral fracture
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