摘要
目的 建立聚桂醇注射液的药物利用评价(DUE)标准,评价其临床使用情况,为临床合理应用聚桂醇提供参考。方法 以聚桂醇注射液药品说明书、相关指南和文献为基础,采用专家咨询法制定DUE标准细则,回顾性评价西安交通大学医学部附属三二〇一医院2021年1月—2022年8月住院患者聚桂醇注射液的使用情况。结果共纳入143份病历,聚桂醇注射液用药合理的病例有48例(33.57%)。不合理用药主要表现为适应证不适宜(65.03%)和用法用量不适宜(1.40%),适应证不适宜主要为存在超说明书用药。结论 建立的聚桂醇注射液DUE标准细则对临床合理使用该药有一定的参考作用。该院聚桂醇注射液临床应用中尚存在一些问题,应制订相应的干预措施,优化其临床应用,促进合理用药。
Objective To establish the drug use evaluation(DUE)standard of lauromacrogol,evaluate its clinical use,and provide a reference for rational clinical application.Methods Based on the drug instructions,related relevant guidelines and literature of lauromacrogol,the DUE standard was formulated through the expert consultation method.A retrospective study was conducted to evaluate the drug utilization of lauromacrogol in hospitalized patients in 3201 Hospital of Xi’an Jiaotong University in Shaanxi province from January 2021 to August 2022.Results A total of 143 medical records were included,48(33.57%)of which fully met the evaluation criteria.Unreasonable use was mainly manifested as inappropriate indications(65.03%)and unsuitable usage and dosage(1.40%).The unreasonable indications are mainly due to the existence of off-label medication.Conclusion The established DUE standard of lauromacrogol has a certain reference effect on the rational use of lauromacrogol in clinical practice.Irrational usages still exists in the clinical application of lauromacrogol in the hospital,and interventions should be developed to optimize its clinical application and promote the rational drug use.
作者
胡甜
贾莉
崔艳华
武蕊
张进华
HU Tian;JIA Li;CUI Yanhua;WU Rui;ZHANG Jinhua(Department of Pharmacy,3201 Hospital of Xi’an Jiaotong University Health Science Center,Hanzhong 723000,Shaanxi Province,China;Department of Pharmacy,Xinjiang Uygur Autonomous Region People's Hospital,Urumchi 830000,China;Department of Pharmacy,Fujian Maternity and Child Health Care Hospital,Fuzhou 350001,China)
出处
《药物流行病学杂志》
CAS
2024年第5期500-507,共8页
Chinese Journal of Pharmacoepidemiology
