摘要
胃癌是最常见的胃恶性肿瘤,且在我国的发病率越来越高。大部分患者确诊胃癌已处于晚期,治疗效果差,死亡率高。早期胃癌患者的治疗效果及预后优于晚期胃癌患者,早诊断、早治疗成为胃癌诊治的关键。目前,早期胃癌的诊断金标准是活组织检查,但此种方法属于侵入性检查,给患者带来较大痛苦,费用较高且容易漏诊,不适合作为筛查手段。检测血清标志物这种非侵入性检查方法,为早期胃癌的诊断提供了新的策略。本文就血清标志物在早期胃癌检测中的研究进展作一综述。
Gastric cancer is the most common gastric malignant tumor,and the incidence is getting higher in our country.Most patients are diagnosed with gastric cancer when it is in the advanced stage with poor treatment effect and high mortality.The therapeutic effect and prognosis of patients with early gastric cancer are better than those with advanced gastric cancer,so early diagnosis and treatment become the key to the diagnosis and treatment of gastric cancer.At present,the gold standard for the diagnosis of early gastric cancer is biopsy,which is invasive,painful to patients,expensive and easy to miss,so it is not suitable as a screening method.Detection of serum markers,a non-invasive method,provides a new strategy for the diagnosis of early gastric cancer.This article reviews the progress of serum markers in the detection of early gastric cancer.
作者
王玉琪
葛剑
陈娜
WANG Yuqi;GE Jian;CHEN Na(Department of Gastroenterology,Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China)
出处
《山东第一医科大学（山东省医学科学院）学报》
CAS
2024年第6期372-377,共6页
Journal of Shandong First Medical University ＆ Shandong Academy of Medical Sciences
基金
山东省自然科学基金(ZR2020MH255)。
关键词
早期胃癌
检测
血清
生物标志物
early gastric cancer
detection
serum
biomarkers
