摘要
乳腺癌发病率位居女性恶性肿瘤发病率之首。近年来越来越多的研究表明肠道微生态与乳腺癌的发生密切相关。中医理论中“从脾论治”涉及“脾主运化、脾主升清、脾藏意主思、脾为之卫”诸多方面,肠道菌群与上述生理职能具有颇高相似性。故本文基于肠道菌群探讨从脾论治乳腺癌的科学内涵,为中医学从脾论治乳腺癌提供分子机制层面的依据,以期拓宽乳腺癌的中西医诊疗思路。
Breast cancer is a global problem that jeopardizes women's health,and its incidence ranks the first female malignant tumors.Recently,more and more studies have shown a significant association between intestinal microecology and the development of breast cancer.In Chinese medicine theory,“treating from the spleen”involves“the spleen is the master of transportation,the spleen is the master of ascending and clearing,the spleen is the master of thinking,and the spleen is the guardian”,and the intestinal microecology has a high similarity with the above physiological functions.Therefore,based on the intestinal flora,this article would discuss the scientific connotation of treating breast cancer with the spleen theory,and provide the molecular mechanism of breast cancer treatment with the spleen theory for Chinese medicine,with the aim of broadening the ideas of Chinese and Western medical diagnosis and treatment of breast cancer.
作者
孙心悦
葛梦迪
王宽宇
贺紫薇
SUN Xinyue;GE Mengdi;WANG Kuanyu;HE Ziwei(Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang 150040,China;不详)
出处
《中国临床研究》
CAS
2024年第5期788-792,共5页
Chinese Journal of Clinical Research
基金
黑龙江省自然科学基金面上项目(H2018054)
黑龙江省级名中医专家传承工作室建设项目(〔2020〕55号)
黑龙江省卫生健康委科研课题(20220404010995)
黑龙江省中医药科研项目(ZHY2022-002)。
关键词
肠道菌群
乳腺癌
从脾论治
雌激素
表观遗传
微生物群
Intestinal flora
Breast cancer
Treatment from spleen
Estrogen
Epigenetic inheritance
Microbiota
