摘要
目的 以老年人为研究对象,探讨血红蛋白浓度与代谢综合征(MetS)及其组分患病的关系,进而为老年人MetS的防治提供科学依据。方法 选择2021-01-01-12-31在青岛市某区社区卫生服务中心进行健康体检的≥65岁老年人作为研究对象,共纳入35 966名老年人,按照血红蛋白浓度的三分位数分为T_(1)(<132 g/L)、T_(2)(132~144 g/L)和T_(3)(≥144 g/L)3个组,采用logistic回归分析血红蛋白对MetS及其组分患病的影响。结果 MetS患者18 202例,患病率为50.60%;MetS组的腰围(t=71.23,P<0.001)、收缩压(t=50.66,P<0.001)、舒张压(t=29.51,P<0.001)、三酰甘油(t=68.01,P<0.001)、空腹血糖(t=63.17,P<0.001)、血红蛋白(t=24.12,P<0.001)水平高于非MetS组,但MetS组的高密度脂蛋白胆固醇含量低于非MetS组(t=27.19,P<0.001),差异均有统计学意义。logistic回归分析结果表明,在控制混杂因素后,血红蛋白T_(2)组患MetS(95%CI:1.80~2.01)、腹型肥胖(95%CI:1.52~1.73)、高血压(95%CI:1.31~1.51)、高血糖(95%CI:1.47~1.64)和血脂异常(95%CI:1.28~1.44)的风险分别是T_(1)组的1.91、1.62、1.41、1.44和1.36倍,均P<0.001;血红蛋白T_(3)组患MetS(95%CI:2.09~2.34)、腹型肥胖(95%CI:1.84~2.12)、高血压(95%CI:1.53~1.77)、高血糖(95%CI:1.56~1.74)和血脂异常(95%CI:1.33~1.49)的风险分别是T1组的2.21、1.98、1.65、1.64和1.41倍,均P<0.001。结论 血红蛋白浓度与MetS及其组分患病相关,血红蛋白水平可以作为老年人MetS及其组分患病的临床预测指标。
Objective To explore the relationship between hemoglobin concentration and metabolic syndrome(MetS)and its components in elderly individuals,and to provide a scientific basis for the prevention and treatment of MetS in the elderly.Methods A total of 35966elderly people aged≥65who underwent health examinations at a community health service center in a certain district of Qingdao from January 1to December 31,2021were selected as the research subjects.According to the third percentile of hemoglobin concentration,they were divided into three groups:T_(1)(<132g/L),T_(2)(132-144g/L),and T_(3)(≥144g/L).Logistic regression analysis was used to investigate the impact of hemoglobin on MetS and its components.Results There were 18202MetS patients,with a prevalence rate of 50.60%.The waist circumference(t=71.23,P<0.001),systolic blood pressure(t=50.66,P<0.001),diastolic blood pressure(t=29.51,P<0.001),triglycerides(t=68.01,P<0.001),fasting blood glucose(t=63.17,P<0.001),and hemoglobin(t=24.12,P<0.001)levels in the MetS group were higher than those in the non MetS group,but the high-density lipoprotein cholesterol content in the MetS group was lower than that in the non MetS group(t=27.19,P<0.001),and the differences were statistically significant.The results of logistic regression analysis showed that after controlling for confounding factors,the risk of MetS(95%CI:1.80-2.01),abdominal obesity(95%CI:1.52-1.73),hypertension(95%CI:1.31-1.51),hyperglycemia(95%CI:1.47-1.64),and dyslipidemia(95%CI:1.28-1.44)in the hemoglobin T_(2)group was 1.91,1.62,1.41,1.44,and 1.36times higher than that in the T_(1)group,respectively,with all P<0.001.The risk of MetS(95%CI:2.09-2.34),abdominal obesity(95%CI:1.84-2.12),hypertension(95%CI:1.53-1.77),hyperglycemia(95%CI:1.56-1.74),and dyslipidemia(95%CI:1.33-1.49)in the T_(3)group was 2.21,1.98,1.65,1.64,and 1.41times higher than that in the T_(1)group,respectively,with all P<0.001.Conclusion Hemoglobin is associated with MetS and its components,and hemoglobin levels can serve as a clinical predictive indicator for MetS and its components in the elderly.
作者
邵宇涵
苏健
肖海青
邵珠刚
刘丽
SHAO Yuhan;SU Jian;XIAO Haiqing;SHAO Zhugang;Liu Li(Qingdao Municipal Center for Disease Control and Prevention,Qingdao Institute of Preventive Medicine,Qingdao,Shandong 266033,China;Shandong Muhua Medical Technology Co.,Ltd.,Qingdao,Shandong 266000,China)
出处
《社区医学杂志》
CAS
2024年第5期143-147,共5页
Journal Of Community Medicine
基金
青岛市科技惠民示范引导专项(21-1-4-rkjk-1-nsh)
青岛市医疗卫生优秀人才培养项目。
关键词
代谢综合征
血红蛋白
老年人
腹型肥胖
高血压
高血糖
血脂异常
metabolic syndrome
hemoglobin
the elderly
abdominal obesity
hypertension
hyperglycemia
dyslipidemia
