摘要
目的探讨慢性阻塞性肺疾病(COPD)患者支气管管壁厚度(T)和管壁面积占总气道总截面百分比(WA%)与肺一氧化碳弥散量(DLco)的相关性。方法选取我院2019年1月至2021年12月收治的100例COPD患者,其中COPD轻度40例、中度25例、重度23例和极重度12例;与50名健康体检者进行对照,测量支气管的T、WA%及DLco,分析支气管的T、WA%与DLco之间的相关性。结果COPD轻度、中度、重度和极重度与对照组的T、WA%、DLco具有显著性差异(P<0.05);COPD轻度、中度、重度和极重度四组的T和WA%随着COPD疾病的加剧逐渐增加;COPD轻度、中度、重度和极重度四组的DLco随着COPD疾病的加剧逐渐降低;COPD组的T与DLco具有显著的正相关关系(P<0.05),COPD组的WA%与DLco具有显著的正相关关系,差异有统计学意义(P<0.05)。结论COPD患者的T、WA%比健康人高,DLco比健康人低,COPD患者的T、WA%均与DLco呈显著正相关关系,T、WA%和DLco3个指标的变化情况可预测COPD病情的发展。
Objective To investigate the correlation between the bronchial wall thickness(T)and the percentage of wall area in total airway section(WA%)in patients with chronic obstructive pulmonary disease(COPD)and carbon monoxide diffusion volume(DLco).Methods 100 patients with COPD admitted in our hospital from January 2019 to December 2021,including 40 patients with mild COPD,25 patients with moderate COPD,23 patients with severe COPD and 12 patients with very severe COPD,were compared with 50 normal people.T,WA%and DLco of bronchi were measured,and the correlation between T,WA%and DLco of bronchi was analyzed.Results There were statistically significant differences in T,WA%and DLco between mild,moderate,severe and extremely severe COPD and control group(P<0.05).T and WA%of mild,moderate,severe and extremely severe COPD groups increased gradually with the exacerbation of COPD disease.DLco in mild,moderate,severe and extremely severe COPD groups decreased gradually with the exacerbation of COPD.There was a significant positive correlation between T and DLco in COPD group(P<0.05),and a significant positive correlation between WA%and DLco in COPD group(P<0.05).Conclusion The percentage of T and WA%in patients with COPD is higher than that in healthy people,and the percentage of DLco in patients with COPD is lower than that in healthy people.
作者
曹亚娟
王警建
金晨望
Cao Yajuan;Wang JingJian;Jin Chenwang(Imaging Center,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710000,Shanxi,China;Department of Imaging,The Ninth Hospital of Xi’an,Xi’an 710000,Shanxi,China;CT Room,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710000,Shanxi,China)
出处
《贵州医药》
CAS
2024年第6期862-864,共3页
Guizhou Medical Journal
