期刊文献+

腹腔镜右半结肠癌完整结肠系膜切除术与传统开腹右半结肠癌根治术的临床对比研究

下载PDF
导出
摘要 目的探讨腹腔镜右半结肠癌完整结肠系膜切除术(CME)与传统开腹右半结肠癌根治术的临床效果。方法回顾性分析2019-08—2022-10郑州市金水区总医院普外科行手术治疗的86例右半结肠癌患者的临床资料,根据手术方法分为腹腔镜右半结肠癌CME根治术组(腔镜组,45例)和传统开腹手术组(开腹组,41例)。比较2组患者的基线资料、围术期指标,以及并发症发生率。采用视觉模拟评分法(VAS)评分评价2组患者术后疼痛程度。分别与术前及术后第4周检测2组患者的CD3^(+)、CD4^(+)、CD8^(+)T淋巴细胞水平,并计算CD4^(+)/CD8^(+)。统计术后1 a期间的生存与复发率。结果2组手术时间差异无统计学意义(P>0.05)。腔镜组患者的术中出血量少于开腹组,淋巴结清扫数目多于开腹组,术后肛门首次排气时间短于开腹组,术后第1天的VAS评分低于开腹组,术后并发症发生率低于开腹组。差异均有统计学意义(P<0.05)。术后2组患者的CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)均较术前升高,CD8^(+)较术前降低。其中,与开腹组相比,腔镜组CD3^(+)、CD4^(+)、CD4^(+)/CD8更高,CD8^(+)更低。差异有统计学意义(P<0.05)。术后1 a内腔镜组患者的生存率高于开腹组,复发率低于开腹组,差异均有统计学意义(P<0.05)。结论与传统开腹右半结肠癌根治术比较,腹腔镜右半结肠癌CME根治术在优化围术期指标、减少并发症风险、改善机体免疫功能,以及提升生存率和降低复发率方面更具有优势。
出处 《河南外科学杂志》 2024年第3期64-67,共4页 Henan Journal of Surgery
  • 相关文献

参考文献11

二级参考文献111

  • 1赵东兵,单毅,王成峰,吴健雄,邵永孚,赵平.伴有同时性肝转移结直肠癌的外科治疗[J].中华肿瘤杂志,2007,29(7):552-554. 被引量:7
  • 2Merkel,S,Mansmann,U,Papadopoulos,T,Wittekind,C,Hohenberger,W,Hermanek,P.The prognostic inhomogeneity of colorectal carcinomas stage III: a proposal for subdivision of stage III. Cancer . 2001
  • 3David G. Jayne,Pierre J. Guillou,Helen Thorpe,Philip Quirke,Joanne Copel,Adrian M.H. Smith,Richard M. Heath,Julia M. Bro.Randomized Trial of Laparoscopic-Assisted Resection of Colorectal Carcinoma: 3-Year Results of the UK MRC CLASICC Trial Group. Japanese Journal of Clinical Oncology . 2007
  • 4E. Cotte,P. Peyrat,E. Piaton,F. Chapuis,M. Rivoire,O. Glehen,C. Arvieux,J.-Y. Mabrut,J. Chipponi,F.-N. Gilly.Lack of prognostic significance of conventional peritoneal cytology in colorectal and gastric cancers: Results of EVOCAPE 2 multicentre prospective study[J].European Journal of Surgical Oncology.2013(7)
  • 5Helen M. Mohan,Donal B. O’Connor,James M. O’Riordan,Des C. Winter.Prognostic significance of detection of microscopic peritoneal disease in colorectal cancer: A systematic review[J].Surgical Oncology.2013
  • 6Paolo Sammartino,Simone Sibio,Daniele Biacchi,Maurizio Cardi,Fabio Accarpio,Pietro Mingazzini,Maria Sofia Rosati,Tommaso Cornali,Angelo Di Giorgio,Paul H. Sugarbaker.Prevention of Peritoneal Metastases from Colon Cancer in High-Risk Patients: Preliminary Results of Surgery plus Prophylactic HIPEC[J].Gastroenterology Research and Practice.2012
  • 7P. Sammartino,S. Sibio,D. Biacchi,M. Cardi,P. Mingazzini,M. S. Rosati,T. Cornali,B. Sollazzo,J. Maherfouad Atta,A. Giorgio.Long-term results after proactive management for locoregional control in patients with colonic cancer at high risk of peritoneal metastases[J]. International Journal of Colorectal Disease . 2014 (9)
  • 8Yoichiro Homma,Takashi Hamano,Yasuhiro Akazawa,Yoshiro Otsuki,Shinichi Shimizu,Hiroshi Kobayashi,Shingo Kameoka,Yasuyuki Kobayashi.Positive peritoneal washing cytology is a potential risk factor for the recurrence of curatively resected colorectal cancer[J]. Surgery Today . 2014 (6)
  • 9Diane Goéré,David Malka,Dimitri Tzanis,Vinicius Gava,Valérie Boige,Clarisse Eveno,Léon Maggiori,Frédéric Dumont,Michel Ducreux,Dominique Elias.Is There a Possibility of a Cure in Patients With Colorectal Peritoneal Carcinomatosis Amenable to Complete Cytoreductive Surgery and Intraperitoneal Chemotherapy?[J]. Annals of Surgery . 2013 (6)
  • 10Prognostic Significance of Free Peritoneal Tumor Cells in the Peritoneal Cavity Before and After Neoadjuvant Chemotherapy in Patients with Gastric Carcinoma Undergoing Potentially Curative Resection[J]. Annals of Surgical Oncology . 2010 (10)

共引文献579

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部