摘要
目的 探讨慢性阻塞性肺气肿的临床症状及治疗效果。方法 选取100例慢性阻塞性肺气肿患者为研究对象,按照随机数字表原则将患者分为对照组及观察组,每组50例。对照组应用常规治疗,观察组在对照组的基础上联用泼尼松片治疗。比较两组患者的临床症状评分,临床治疗效果,用药不良反应发生情况。结果 用药7 d后,观察组患者的胸闷、呼吸困难、咳痰、嗜睡评分分别为(0.85±0.21)、(0.90±0.24)、(0.81±0.20)、(0.88±0.26)分,低于对照组的(1.27±0.28)、(1.34±0.35)、(1.23±0.25)、(1.20±0.31)分,比较有差异(P<0.05)。观察组临床治疗总有效率98.00%大于对照组的80.00%,比较有差异(P<0.05)。两组患者的用药不良反应发生率比较无差异(P>0.05)。结论 慢性阻塞性肺气肿发生后,常规治疗的同时联合应用泼尼松片治疗,可有效改善临床症状,提高治疗效果,还可保障治疗安全性。
Objective To explore the clinical symptoms and therapeutic effect of chronic obstructive emphysema.Methods A total of 100 patients with chronic obstructive emphysema were selected as the study subjects and divided into a control group and an observation group according to the principle of random number table,with 50 cases in each group.The control group was treated with conventional treatment,and the observation group was treated with prednisone tablets on the basis of the control group.The clinical symptom score,clinical therapeutic effect and occurrence of adverse drug reactions were compared between the two groups.Results After 7 d of medication,the scores of chest tightness,dyspnea,sputum and lethargy in the observation group were(0.85±0.21),(0.90±0.24),(0.81±0.20)and(0.88±0.26)points,which were lower than(1.27±0.28),(1.34±0.35),(1.23±0.25)and(1.20±0.31)points in the control group,and there were significant differences(P<0.05).The total effective rate of the observation group was 98.00%,which was higher than 80.00%of the control group,and there was a significant difference(P<0.05).There was no difference in the incidence of adverse drug reactions between the two groups(P>0.05).Conclusion Conventional treatment combined with prednisone tablets in the treatment of chronic obstructive emphysema can effectively improve the clinical symptoms,improve the therapeutic effect,and ensure the safety of treatment.
作者
赵金牛
崔连明
孙长亮
ZHAO Jin-niu;CUI Lian-ming;SUN Chang-liang(Yangxin County Hospital of Traditional Chinese Medicine,Binzhou 251800,China)
出处
《中国实用医药》
2024年第10期106-108,共3页
China Practical Medicine
关键词
慢性阻塞性肺气肿
临床症状评分
泼尼松片
治疗效果
用药不良反应
Chronic obstructive emphysema
Clinical symptom score
Prednisone tablets
Therapeutic effect
Adverse drug reactions
