摘要
本文的目的是研究牙周炎对2型糖尿病患者的胰岛素抵抗及其相关生化指标的影响。将哈尔滨市双城区人民医院2023年6月至2023年12月收集的100名2型糖尿病患者分为两组,其中50名患有牙周炎,另外50名没有牙周炎。通过回顾性分析病历资料,对比两组患者的空腹血糖(FBG)、糖化血红蛋白(HbA1c)、胰岛素抵抗指数(HOMA-IR)、C反应蛋白(CRP)和总胆固醇(TC)等生化指标。研究结果表明,有牙周炎的2型糖尿病患者比无牙周炎的患者在FBG、HbA1c和HOMA-IR上数值更高,且CRP水平亦较高,表明存在更明显的炎症状态和胰岛素抵抗。此外,牙周炎组的TC水平也略有升高。这些结果暗示牙周炎可能通过促进炎症和胰岛素抵抗的机制加重2型糖尿病的病情。根据这些发现,建议2型糖尿病患者应加强口腔卫生管理,以减少牙周炎的发生,从而改善糖尿病的代谢控制。
The purpose of this paper is to study the effect of periodontitis on insulin resistance and related biochemical indicators in patients with type 2 diabetes.100 type 2 diabetes patients collected by Harbin Shuangcheng District People's Hospital from June 2023 to December 2023 were divided into two groups,50 of whom had periodontitis and the other 50 had no periodontitis.By retrospectively analyzing medical records,compare the biochemical indicators of fasting blood glucose(FBG),glycated hemoglobin(HbA1c),insulin resistance index(HOMA-IR),C-reactive protein(CRP),and total cholesterol(TC)between two groups of patients.The research results show that type 2 diabetes patients with periodontitis have higher FBG,HbA1c and HOMA-IR values than patients without periodontitis,and CRP levels are also higher,indicating that there is a more obvious inflammatory state and insulin resistance.In addition,the TC level in the periodontitis group also slightly increased.These results suggest that periodontitis may aggravate the condition of type 2 diabetes by promoting inflammation and insulin resistance.According to these findings,it is suggested that patients with type 2 diabetes should strengthen oral health manage-ment to reduce the occurrence of periodontitis and improve the metabolic control of diabetes.
作者
邓志凯
杨孟泽
Zhikai Deng;Mengze Yang(Harbin Medical University,Harbin,Heilongjiang 150076)
关键词
牙周炎
2型糖尿病
生化指标
periodontitis
type 2 diabetes
biochemical indicators
