摘要
尿酸作为嘌呤代谢的最终产物,不仅是引起痛风的原因,还可能在心血管疾病的发生发展中有重要作用,一些临床研究已经报道了血清尿酸作为心血管预后的预测指标。目前高尿酸血症与心血管疾病的因果关系仍然存在争议,但降尿酸治疗作为临床实践中一个潜在治疗靶点及其良性收益已逐步得到重视。本文综述了目前关于高尿酸血症与心血管疾病的研究进展。
As the final product of purine metabolism,uric acid is not only the cause of gout,but also may play an important role in the occurrence and development of cardiovascular diseases.Some clinical studies have reported that serum uric acid is a predictor of cardiovascular prognosis.At present,the causal relationship between hyperuricemia and cardiovascular diseases is still controversial,but as a potential therapeutic target in clinical practice,lowering uric acid treatment and its benign benefits have gradually received attention.This article reviews the current research progress of hyperuricemia and cardiovascular diseases.
作者
何喆
张蕊
HE Zhe;ZHANG Rui(Blood Purification Center,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150081,China)
出处
《心血管康复医学杂志》
CAS
2024年第3期376-379,共4页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
高尿酸血症
心血管疾病
预后
危险因素
Hyperuricemia
Cardiovascular diseases
Prognosis
Risk factors
