摘要
目的探究迷走神经刺激术(VNS)治疗超难治性癫痫持续状态(SRSE)的疗效。方法纳入2例分别于2012年2月28日和2020年6月10日在首都医科大学三博脑科医院行VNS的SRSE患者,分析其临床特征及手术疗效。结果2例患者术中情况良好,病例1于刺激器开机1周后癫痫持续状态(SE)消失,术后7年随访提示未再发生SE且癫痫发作频率减少50%;病例2于刺激器开机1个月后SE消失,术后2年随访提示未再发生SE且癫痫发作频率减少80%。结论VNS是治疗SRSE的安全有效手段。
Objective To investigate the efficacy of vagus nerve stimulation(VNS)in the treatment of super-refractory status epilepticus(SRSE).Methods 2 patients diagnosed with SRSE,who underwent VNS on February 28,2012 and June 10,2020 in Sanbo Brain Hospital,Capital Medical University,were included to analyze their clinical characteristics and surgical efficacy respectively.Results 2 patients were in good condition intraoperatively.Case 1 had disappearance of status epilepticus(SE)1 week after the stimulator was turned on,and the 7-year postoperative follow-up suggested no recurrence of SE and 50%reduction in seizure frequency.Case 2 had disappearance of SE 1 month after the stimulator was turned on,and the 2-year postoperative follow-up revealed no recurrence of SE and an 80%reduction in seizure frequency.Conclusion VNS is a safe and effective treatment for SRSE.
作者
彭鑫涛
孙卫进
马凯强
王雄飞
周健
王梦阳
王静
李天富
栾国明
关宇光
PENG Xintao;SUN Weijin;MA Kaiqiang;WANG Xiongfei;ZHOU Jian;WANG Mengyang;WANG Jing;LI Tianfu;LUAN Guoming;GUAN Yuguang(Department of Neurosurgery,Sanbo Brain Hospital,Capital Medical University,Beijing 100093,China;不详)
出处
《临床神经外科杂志》
2024年第3期262-266,共5页
Journal of Clinical Neurosurgery
基金
国家重点研发计划课题(2021YFC2401203)。
