摘要
目的:观察穴位埋线联合涤浊化瘀方治疗肥胖型非酒精性脂肪性肝病(NAFLD)的临床疗效。方法:选取84例肥胖型NAFLD患者作为研究对象,按随机数字表法分为治疗组和对照组,每组42例,两组患者均给予涤浊化瘀方和健康宣教,治疗组患者在此基础上采取穴位埋线治疗,每2周1次,疗程12周。比较两组患者治疗前后体质量指数(BMI)、腰围、体质量、血脂水平、肝功能、受控衰减参数(CAP)值和中医证候积分的变化情况。结果:治疗组患者治疗后BMI、腰围、体质量、CAP值明显低于治疗前(P<0.05),两组患者治疗后BMI、腰围、CAP值均明显下降,治疗组下降更明显(P<0.05);两组患者治疗后甘油三酯(TG)、总胆固醇(TC)水平明显低于治疗前(P<0.05);治疗组患者治疗后丙氨酸氨基转移酶(ALT)、γ谷胺酰转肽酶(GGT)水平明显低于治疗前,对照组患者治疗后GGT水平明显低于治疗前(P<0.05);两组患者治疗后中医证候积分均明显改善,治疗组患者在改善胁痛、痰多口黏、大便黏腻方面优于对照组(P<0.05);治疗组总有效率97.6%,对照组总有效率88.1%,差异有统计学意义(P<0.05)。结论:对肥胖型NAFLD患者采用穴位埋线联合涤浊化瘀方治疗可有效提高临床疗效,明显改善患者临床症状,降低BMI、腰围、体重、血脂、肝功能、CAP值等指标。
Objective:To observe the clinical efficacy of acupoint catgut embedding combined with Dizhuo Huayu Formula in the treatment of obese non-alcoholic fatty liver disease.Methods:A total of 84 obese patients with non-alcoholic fatty liver disease(NAFLD)were selected as the subjects of the study and randomly divided into a treatment group and a control group,each with 42 cases.Both groups were given Dizhuo Huayu Formula and health education.On this basis,the treatment group received acupoint embedding therapy,once every 2 weeks,for a total of 12 weeks.Compare the changes in body mass index(BMI),waist circumference(WC),body weight,blood lipids,liver function,controlled attenuation parameters(CAP)values,and traditional Chinese medicine syndrome scores between the two groups before and after treatment.Results:After treatment,the BMI,waist circumference,body mass level,and CAP values of the treatment group were significantly lower than before treatment,with a statistically significant difference(P<0.05).The BMI,waist circumference,and CAP values of the two groups decreased significantly after treatment,and the treatment group was superior to the control group(P<0.05).After treatment,the levels of TG and TC in both groups were significantly lower than before treatment(P<0.05).The levels of ALT and GGT in the treatment group after treatment were significantly lower than before treatment,with significant statistical differences(P<0.05).The levels of GGT in the control group after treatment were significantly lower than before treatment,with significant statistical differences(P<0.05).After treatment,both groups showed significant improvement in traditional Chinese medicine syndrome scores.The treatment group was superior to the control group in improving symptoms of flank pain,phlegm and sticky mouth,and sticky stool(P<0.05);The total effective rate of the treatment group was 97.6%,while the total effective rate of the control group was 88.1%,with a statistically significant difference(P<0.05).Conclusion:In patients with NAFLD characterized by obesity,the therapeutic approach combining acupoint thread embedding with the herbal formula for purifying and resolving stasis has been shown to significantly enhance clinical outcomes.This treatment not only markedly alleviates clinical symptoms but also effectively reduces clinical indices such as BMI,WC,body weight,blood lipids,liver function,and CAP values.
作者
赵婷婷
赵文霞
张丽慧
张峰
刘素彤
顾亚娇
ZHAO Ting-ting;ZHAO Wen-xia;ZHANG Li-hui(The First Affiliated Hospital of Henan University of CM(Zhengzhou Henan,450000),China)
出处
《中西医结合肝病杂志》
CAS
2024年第6期517-520,共4页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金
河南省中医学“双一流”创建科学研究专项(No.HSRP-DFCTCM-2023-3-13)
河南省中医药科研专项(No.2021JDZX016)。
关键词
非酒精性脂肪性肝病
穴位埋线
涤浊化瘀方
肥胖
acupoint catgut embedding
Dizhuo Huayu formula
obesity
non alcoholic fatty liver disease
