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清化承气汤治疗急性脑梗死痰热腑实证临床研究

Qinghua Chengqi Decoction in the Treatment of Acute Cerebral Infarction with Phlegm Heat and Fu-viscera Excess Syndrome
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摘要 目的研究急性脑梗死痰热腑实证应用清化承气汤的临床疗效。方法纳入江西省靖安县中医院2020年1月—2021年12月收治的急性脑梗死患者102例,经随机数字表法分为观察组和对照组,每组51例。对照组给予西医治疗,观察组在对照组基础上加用清化承气汤治疗。对比两组治疗前后中医证候评分,全血低切黏度、全血高切黏度、血浆黏度、纤维蛋白原水平,总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平以及临床疗效。结果观察组总有效率为90.20%(46/51),显著高于对照组的70.59%(36/51)(P<0.05)。治疗后,两组中医证候内火、痰湿、阴虚评分以及总分,全血低切黏度、全血高切黏度、血浆黏度、纤维蛋白原水平及TC、TG、HDL-C、LDL-C水平均较治疗前显著改善,且观察组显著低于对照组(P<0.05)。结论急性脑梗死痰热腑实证患者应用清化承气汤疗效确切,可明显恢复神经功能、改善症状、降低血液黏度及血脂水平。 Objective To study the clinical efficacy of Qinghua Chengqi decoction in the treatment of acute cerebral infarction with phlegm heat and fu-viscera excess syndrome.Methods A total of 102 patients with acute cerebral infarction diagnosed and admitted to Jing’an County Hospital of Traditional Chinese Medicine from January 2020 to December 2021 were randomly divided into an observation group and a control group using a random number table method,with 51 patients in each group.The control group was treated with Western medicine,while the observation group was treated with Qinghua Chengqi decoction on the basis of the control group.The therapeutic effects of two groups,including TCM syndrome scores before and after treatment,whole blood low shear viscosity,whole blood high shear viscosity,plasma viscosity,fibrinogen levels,and TC,TG,HDL-C and LDL-C levels was compared.Results The total effective rate of the observation group was 90.20%(46/51),which was significantly higher than 70.59%(36/51)of the control group(P<0.05).After treatment,the scores of internal fire,phlegm dampness,yin deficiency and total scores improved significantly compared with before treatment,and the improvement of the above scores in the observation group was significantly better than that in the control group(P<0.05).After treatment,all indicators of whole blood low shear viscosity,whole blood high shear viscosity,plasma viscosity,fibrinogen levels,and the levels of TC,TG,HDL-C and LDL-C improved significantly,and the improvement of the above indicators in the observation group was significantly better than that in the control group(P<0.05).Conclusion The application of Qinghua Chengqi decoction in the treatment of phlegm heat and fu-viscera excess syndrome in acute cerebral infarction has a definite therapeutic effect,can significantly restore neurological function,improve symptoms,and reduce blood viscosity and blood lipid levels.
作者 王细文 WANG Xiwen(Department of Neurology,Jing’an County Hospital of Traditional Chinese Medicine,Jiangxi Province,Yichun 330699,China)
出处 《中国中医药现代远程教育》 2024年第15期99-102,共4页 Chinese Medicine Modern Distance Education of China
关键词 中风 急性脑梗死 痰热腑实证 清化承气汤 中医药疗法 stroke acute cerebral infarction phlegm heat and fu-viscera excess syndrome Qinghua Chengqi decoction therapy of traditional Chinese medicine
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