摘要
目的探讨津力达颗粒联合门冬胰岛素治疗妊娠糖尿病的临床效果。方法选取寿光市人民医院2020年1月至2022年12月收治的76例妊娠糖尿病患者作为研究对象,采用随机数字表法分为对照组(38例)与观察组(38例)。对照组采用门冬胰岛素治疗,观察组在对照组基础上联合津力达颗粒治疗。比较两组母婴结局、临床指标水平及临床症状评分。结果观察组产后出血、巨大儿、剖宫产和胎盘早剥的发生率均低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组餐后2h血糖、空腹血糖、空腹胰岛素及胰岛素抵抗指数水平均低于对照组,胰岛素β细胞功能水平高于对照组,差异有统计学意义(P<0.05)。两组神疲、腰膝酸困、气短、夜尿频多和乏力评分均低于对照组,差异有统计学意义(P<0.05)。结论津力达颗粒联合门冬胰岛素治疗妊娠糖尿病的临床效果显著,值得推广。
Objective To explore the clinical effect of Jinlida Granules combined with Insulin Aspart in the treatment of gestational diabetes mellitus.Methods A total of 76 patients with gestational diabetes mellitus from January 2020 to December 2022 admitted to Shouguang People’s Hospital were selected as the study objects.All the patients were divided into the control group(38 cases)and the observation group(38 cases)by the random number table method.The control group was treated with Insulin Aspart,and the observation group was treated with Jinlida Granules on the basis of the control group.The maternal and infant outcomes,levels of clinical indicators,and scores of clinical symptoms were compared between the two groups.Results The incidence of postpartum hemorrhage,macrosomia,cesarean section,and placental abruption in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of 2 hours postprandial blood glucose,fasting blood glucose,fasting insulin,and homeostasis model assessment of insulin resistance in the observation group were lower than those in the control group,the level of homeostasis model assessmentβcell function was higher than that in the control group,and the differences were statistically significant(P<0.05).The scores of spiritlessness,soreness and weakness of waist and knees,shortness of breath,frequent nocturia,and fatigue in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The clinical effect of Jinlida Granules combined with Insulin Aspart in the treatment of gestational diabetes mellitus is significant and worth promoting.
作者
张涛
曹双元
张素华
ZHANG Tao;CAO Shuangyuan;ZHANG Suhua(Department of Obstetrics,Shouguang People’s Hospital,Shandong Province,Shouguang 262700,China;Department of Rheumatology,Shouguang People’s Hospital,Shandong Province,Shouguang 262700,China)
出处
《妇儿健康导刊》
2024年第11期88-91,共4页
JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
关键词
津力达颗粒
门冬胰岛素
妊娠糖尿病
Jinlida Granules
Insulin Aspart
Gestational diabetes mellitus
