摘要
目的探讨高压氧联合声光电刺激对颅脑损伤意识障碍患者的促醒作用。方法选取2021年1月至2022年5月南京紫金医院神经康复科130例颅脑损伤意识障碍患者,采用随机数字表法分为对照组65例和研究组65例。对照组接受标准空气加压0.2 MPa(2.0 ATA)吸氧治疗,研究组在每日高压氧治疗结束后进行声光电多重感觉刺激治疗,比较2组患者治疗前后的脑干听觉诱发电位(BAEP)、体感诱发电位(SEP)、格拉斯哥昏迷量表(GCS)评分、中国南京持续性植物状态量表(CNPVSS)评分、临床疗效及并发症发生情况。结果治疗后,2组患者BAEPⅠ、Ⅲ、Ⅴ波及SEP N20波潜伏期均较治疗前缩短,且研究组短于对照组(P<0.05,P<0.01);2组患者GCS和CNPVSS评分均高于治疗前,且研究组高于对照组,差异均有统计学意义(P<0.05,P<0.01);研究组治疗总有效率(88.71%)高于对照组(73.44%),差异有统计学意义(P<0.05)。研究组和对照组的并发症发生率分别为6.45%、10.94%,差异无统计学意义(P>0.05)。结论高压氧联合声光电刺激治疗可有效提高颅脑损伤患者的意识状态量表评分,改善颅脑损伤患者的神经电生理指标,利于患者意识苏醒,提高临床疗效。
Objective To explore the efficacy of hyperbaric oxygen combined with audio-visual-electric stimulation in the treatment of consciousness disorders after traumatic brain injury.Methods From January 2021 to May 2022,a total of 126 patients with consciousness disorders after traumatic brain injury treated in Nanjing Zijin Hospital were selected and randomly divided into a control group of 65 cases and a study group of 65 cases.The control group received 0.2 MPa(2.0 ATA)standard pressurized air therapy.After the daily hyperbaric oxygen therapy,the study group underwent audio-visual-electric multiple sensory stimulation therapy.The results of brain stem auditory evoked potentials(BAEP),somatosensory evoked potentials(SEP)N20,Glasgow coma scale(GCS),and Chinese Nanjing persistent vegetative state scale(CNPVSS)before and after treatment,the clinical efficacy,and the occurrence of complications between the two groups were compared.Results After treatment,the latencies of BAEP I,Ⅲ,and V waves and SEP N20 waves in both groups were shortened compared with those before treatment,with the latencies in the study group shorter than those in the control group during the same period(P<0.05,P<0.01);The GCS and CNPVSS scores in both groups were all higher than those before treatment,and the scores of the study group were higher than those of the control group during the same period,with statistically significant differences(P<0.05,P<0.01);The total effective rate of the study group(88.71%)was higher than that of the control group(73.44%),with a statistically significant difference(P<0.05);The incidence of complications in the study group and control group was 6.45%and 10.94%,respectively,with no statistically significant difference(P>0.05).Conclusion Hyperbaric oxygen combined with audio-visual-electric stimulation therapy can effectively improve the GCS and CNPVSS scores of the patients with traumatic brain injury,improve their neuroelectrophysiological indicators,facilitate consciousness awakening,and improve clinical efficacy.
作者
潘兴明
孙敏
田新佳
王聪
詹婷
王国兴
Pan Xingming;Sun Min;Tian Xinjia;Wang Cong;Zhan Ting;Wang Guoxing(Rehabilitation Department of Nanjing Zijin Hospital,Nanjing 210007,China)
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
2024年第2期192-195,共4页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
关键词
高压氧治疗
声光电刺激
意识障碍
促醒
疗效观察
Hyperbaric oxygen therapy
Audio-visual-electric stimulation
Consciousness disorders
Awakening
Observation of therapeutic effect
