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LncRNA PVT1在胃癌中的研究进展

Progress of LncRNA PVT1 in Gastric Cancer
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摘要 长链非编码RNA浆细胞瘤变异易位体1(Long Non-Coding Ribonucleic Acid Plasmacytoma Variant Translocation 1,LncRNA PVT1)是一种在多种肿瘤中异常表达的LncRNA,与肿瘤的发生、侵袭、患者预后等密切相关。近年来,越来越多的研究表明LncRNA PVT1在胃癌中发挥重要作用。本文将聚焦于LncRNA PVT1在胃癌发生发展及治疗过程中的最新研究进展,探讨并展望其在胃癌的发展及治疗中的价值与可能性。 Long-chain non-coding ribonucleotide plasmacytoma variant translocation 1(LncRNA PVT1)is a kind of LncRNA aberrantly expressed in various tumors and is intimately involved in tumor initiation,invasion,and prognosis of patients.In recent years,accumulating evidence has demonstrated that LncRNA PVT1 plays a pivotal role in the gastric cancer.This review summarized the latest research advances of LncRNA PVT1 in the gastric cancer.It also explored and prospected its potential value and feasibility in the development and treatment of the gastric cancer.
作者 王丹君 卢雨林 张蕾 陈国奥 韩笑 潘泽民 李冬妹 WANG Dan-jun;LU Yu-lin;ZHANG Lei;CHEN Guo-ao;HAN Xiao;PAN Ze-min;LI Dong-mei(Biochemistry department/Key Laboratory of Xinjiang Endemic and Ethnic Diseases,Shihezi University School of Medicine,Xinjiang Shihezi,832002;Clinical laboratory the First Affiliated Hospital of Shihezi University,Xinjiang Shihezi,832008)
出处 《农垦医学》 2024年第2期145-148,172,共5页 Journal of Nongken Medicine
基金 国家自然科学基金项目(82160573) 新疆生产建设兵团指导性科技计划项目(2022ZD084)。
关键词 LncRNA PVT1 胃癌 治疗 预后 LncRNA PVT1 Gastric cancer Treatment Prognosis
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