摘要
目的探讨左甲状腺素钠治疗妊娠合并甲状腺功能减退患者的效果。方法378例妊娠合并甲状腺功能减退患者随机分为两组,对照组采用甲状腺片治疗,观察组采用左甲状腺素钠治疗,对比两组的临床疗效。结果治疗后,观察组的FT_(4)、FT_(3)水平均高于对照组,TSH水平、不良母婴结局发生率均低于对照组(P<0.05)。两组的不良反应发生率对比,差异无统计学意义(P>0.05)。结论左甲状腺素钠治疗妊娠合并甲状腺功能减退患者可有效改善其甲状腺功能与母婴结局。
Objective To explore the effect of levothyroxine sodium in the treatment of pregnancy patients with hypothyroidism.Methods 378 pregnancy patients with hypothyroidism were randomly divided into two groups.The control group was treated with thyroid tablets,and the observation group was treated with levothyroxine sodium.The clinical efficacy was compared between the two groups.Results After treatment,the levels of FT_(4) and FT_(3) in the observation group were higher than those in the control group,and the TSH level and the incidence of adverse maternal and infant outcomes were lower than those in the control group(P<0.05).No significant difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Levothyroxine sodium in the treatment of pregnancy patients with hypothyroidism can effectively improve their thyroid function and maternal and infant outcomes.
作者
于海微
林锦芬
黄团明
YU Haiwei;LIN Jinfen;HUANG Tuanming(Department of Obstetrics and Gynecology,Xiamen Hospital of Traditional Chinese Medicine,Xiamen 361009,China)
出处
《临床医学工程》
2024年第6期685-686,共2页
Clinical Medicine & Engineering
关键词
妊娠
甲状腺功能减退
左甲状腺素钠
甲状腺功能
母婴结局
不良反应
Pregnancy
Hypothyroidism
Levothyroxine sodium
Thyroid function
Maternal and infant outcomes
Adverse reaction
