摘要
经过长期进化,植物病原真菌发展出多种复杂而精妙的侵染宿主策略。在植物与病原菌互作过程中,病原菌致病基因的精准表达与调控起至关重要的作用。表观遗传调控是指通过化学修饰改变染色体上的DNA和蛋白质,从而调控基因表达的过程,包括DNA甲基化、组蛋白甲基化、组蛋白乙酰化以及染色质重塑等。越来越多的证据表明,表观遗传调控在植物病原真菌基因的转录重编程中发挥重要作用,进而影响其发育、环境应激反应、次生代谢物的生物合成和致病性等方面。本文综述了近年来表观遗传调控因子方面的研究进展,包括组蛋白修饰、染色质重塑等在植物病原真菌发育和致病性中的作用,并对当前的研究进行了展望,以期为未来的病害防治研究奠定坚实的理论基础。
Over a long period of evolution,plant pathogenic fungi have developed a wide range of intricate and sophisticated strategies to invade their host plants,and the precise regulation of gene expression is necessary for interactions between plants and these pathogens.Epigenetic regulation refers to the process of altering DNA and proteins on chromosomes through chemical modifications,thereby regulating gene expression.These epigenetic regulations include DNA methylation,histone methylation,histone acetylation,and chromatin remodeling.Increasing evidence suggests that epigenetic regulation plays a crucial role in transcriptional reprogramming of plant pathogenic fungal genes,which affects their development,environmental stress response,biosynthesis of secondary metabolites and pathogenicity.This paper reviewed the recent advancements in epigenetic regulators,including histone modification and chromatin remodeling,and their roles in the development and pathogenicity of plant pathogenic fungi and offered insights into the current research prospects to lay a solid theoretical foundation for future disease control research.
作者
孙子越
陶增
SUN Ziyue;TAO Zeng(Institute of Biotechnology,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou 310058,Zhejiang,China)
出处
《浙江大学学报（农业与生命科学版）》
CAS
CSCD
北大核心
2024年第3期469-480,共12页
Journal of Zhejiang University:Agriculture and Life Sciences
基金
浙江省“十四五”旱粮新品种选育重大科技专项(2021C02064)。
