摘要
目的:探究超声引导介入治疗卵巢子宫内膜样囊肿患者的疗效及血清肿瘤标记物水平。方法:将本院2019年5月至2022年5月收治的80例卵巢子宫内膜样囊肿患者随机分为两组。对照组40例行腹腔镜囊肿剔除术,研究组40例行超声引导介入穿刺治疗。比较两组的临床疗效、手术时间、抗生素使用时间及住院时间;评价两组手术前后的血清肿瘤标志物水平及卵巢功能指标变化,观察两组术后1年的复发率。结果:研究组的临床疗效高于对照组(P<0.05);研究组的手术时间、抗生素使用时间及住院时间短于对照组(P<0.05);术后6个月,研究组的血清糖类抗原125(CA125)、糖类抗原199(CA199)、人附睾蛋白4(HE4)水平均低于对照组(P<0.05);术后6个月,研究组的雌激素(E2)水平低于对照组,卵泡刺激素(FSH)、黄体生成素(LH)水平高于对照组(P<0.05);研究组术后1年的复发率低于对照组(P<0.05)。结论:对卵巢子宫内膜样囊肿患者应用超声引导介入穿刺治疗可增强疗效,降低血清肿瘤标记物水平,改善卵巢功能,降低术后复发率。
Objective:To investigate the efficacy and serum tumor markers levels of patients with ultrasound-guided interventional therapy for ovarian endometrioid cyst.Methods:A total of 80 patients with ovarian endometrioid cyst admitted to our hospital from May 2019 to May 2022 were randomly divided into two groups:40 cases in the control group underwent laparoscopic cystectomy,and 40 cases in the study group underwent ultrasound-guided interventional therapy.The clinical efficacy,operation time,antibiotic use time,and hospital stay were compared between the two groups.The serum tumor marker levels and ovarian function indexes were evaluated before and after the operation.The recurrence rate of the two groups was observed one year after operation.Results:The clinical efficacy of the study group was higher than that of the control group(P<0.05).The operation time,antibiotic usage time,and hospitalization time of the study group were shorter than those of the control group(P<0.05).6 months after the operation,the serum Carbohydra Antigen 125(CA125),Carbohydra Antigen 199(CA199)and Human epididymal protein 4(HE4)levels in the study group were lower than those in the control group(P<0.05).Six months after the operation,estrogen(E2)level in the study group was lower than that in the control group,Follicle Stimulating Hormones(FSH)and Luteinizing Hormones(LH)levels in the study group were higher than those in the control group(P<0.05).The recurrence rate in the study group was lower than that in the control group 1 year after operation(P<0.05).Conclusion:The use of ultrasound-guided invasive puncture in the treatment of patients with adenometrioid cysts of the ovaries can enhance the efficacy and reduce the level of serum tumor markers,improve the function of the ovaries,and reduce the rate of postoperative relapse.
作者
张瑞
任永凤
许延兰
王文彬
ZHANG Rui;REN Yongfeng;XU Yanlan(Bozhou People's Hospital,Anhui Bozhou 236000,China)
出处
《河北医学》
CAS
2024年第6期1031-1035,共5页
Hebei Medicine
基金
2020年度安徽省自然科学基金项目,(编号:1908085MH196)。
关键词
子宫内膜样囊肿
超声引导介入
肿瘤标记物
卵巢功能
复发率
Endometrioid cyst
Ultrasound-guided interventional
Tumor markers
Ovarian function
Recurrence rate
